The Incidence and Treatment of Insulin Resistance Among Men With Erectile Dysfunction
| Status: | Completed |
|---|---|
| Conditions: | Erectile Dysfunction, Endocrine |
| Therapuetic Areas: | Endocrinology, Nephrology / Urology |
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 4/2/2016 |
| Start Date: | July 2005 |
| End Date: | June 2006 |
| Contact: | Sue Worley, RN |
| Email: | sworley@psu.edu |
| Phone: | 717-531-5718 |
The Incidence and Treatment of Insulin Resistance Among Men With Erectile
Determine if men with erectile dysfunction (ED) are more likely to have insulin resistance
compared to healthy controls.
compared to healthy controls.
Insulin is a hormone produced by the body that lets sugar into the cells, where it is used
for energy. Insulin resistance occurs when the body’s cells have a decreased ability to
react to insulin. This leads to an increase in insulin secretion. Over time, insulin
resistance can lead to higher levels of sugar in the blood (diabetes), and can also
contribute to obesity, high blood pressure, high cholesterol levels and heart disease. There
are no simple tests to actually diagnose insulin resistance. Currently, the glucose
tolerance test is used to diagnose IR, but it involves several blood draws over a 2-hour
period. Another purpose of this study is to compare a blood test involving only one blood
draw to the 2-hour glucose tolerance test, which involves several blood draws over a 2-hour
period.
It is well known that diabetes often leads to erectile dysfunction. Because insulin
resistance occurs before diabetes, it is possible that erectile dysfunction may occur in
some individuals while they have insulin resistance, but before they develop diabetes. If
this is true, it might be possible to use erectile dysfunction as a sign of insulin
resistance, which may lead to more timely treatment of insulin resistance and may delay or
prevent the development of diabetes, and the other problems mentioned above.
for energy. Insulin resistance occurs when the body’s cells have a decreased ability to
react to insulin. This leads to an increase in insulin secretion. Over time, insulin
resistance can lead to higher levels of sugar in the blood (diabetes), and can also
contribute to obesity, high blood pressure, high cholesterol levels and heart disease. There
are no simple tests to actually diagnose insulin resistance. Currently, the glucose
tolerance test is used to diagnose IR, but it involves several blood draws over a 2-hour
period. Another purpose of this study is to compare a blood test involving only one blood
draw to the 2-hour glucose tolerance test, which involves several blood draws over a 2-hour
period.
It is well known that diabetes often leads to erectile dysfunction. Because insulin
resistance occurs before diabetes, it is possible that erectile dysfunction may occur in
some individuals while they have insulin resistance, but before they develop diabetes. If
this is true, it might be possible to use erectile dysfunction as a sign of insulin
resistance, which may lead to more timely treatment of insulin resistance and may delay or
prevent the development of diabetes, and the other problems mentioned above.
Inclusion Criteria:
- 18-65 years of age, male,
Exclusion Criteria:
- diabetes, peyronies
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