How Has Glaucoma Affected Your Quality of Life?

You are being asked to participate in this research study because you have glaucoma, which is
the second leading cause of blindness in the world and accounts for 15% of blindness
worldwide. Vision loss caused by glaucoma can significantly worsen your health-related
quality of life. Despite the fact that glaucoma has such a big impact on a large number of
people, research examining the long-term effects of glaucoma-related vision loss on one's
quality of life is scarce.

The purpose of this study is to look at the long-term effect of this condition on your
quality of life so that we may gain valuable information about what factors influence the
quality of life of people with glaucoma. To participate in this study, you will need to allow
us to perform clinical tests on your eyes, to self-report your well-being and health-related
quality of life, and to let us know how well you perform your daily life activities.

Inclusion Criteria:

- Minimum 2-year diagnosis of primary open-angle glaucoma, chronic primary angle-closure
glaucoma or exfoliation glaucoma

- Disk Damage Likelihood Scale stages 5 through 8 with visual field loss

- Age between 21 and 80 years

- Able to understand and speak English

Exclusion Criteria:

- Unlikely to be available for annual ocular examination and reassessment across a
4-year period

- Neurological or musculoskeletal problems that would influence performance on
activities of daily living

- Cognitively impaired, as assessed by a face-to-face Mini-Mental State Examination

- Incisional eye surgery within the past three months

- Laser therapy within the previous month

- Any cause for visual reduction other than glaucoma

- Any medical condition which in the investigator's opinion would preclude the subject
from providing reliable and valid data