Transfusion Requirements During Spinal Surgery for Severe Scoliosis
Status: | Completed |
---|---|
Conditions: | Orthopedic |
Therapuetic Areas: | Orthopedics / Podiatry |
Healthy: | No |
Age Range: | Any - 19 |
Updated: | 11/23/2013 |
Start Date: | August 2009 |
End Date: | March 2014 |
Contact: | Anuradha Patel, MD |
Email: | patelan@umdnj.edu |
Phone: | 973 972-5254 |
An Observational Prospective Study of Transfusion Requirements During Spinal Surgery for Severe Scoliosis
Corrective surgery for scoliosis can result in prolonged operating room time and significant
blood loss. The investigators goal is to determine what the transfusion requirements are for
young adults undergoing spinal surgery for scoliosis and what other intra-operative factors
influence the amount of blood and blood products used. The investigators will used the
information obtained to improve the management of patients undergoing corrective surgery for
scoliosis.
Data collected prior to surgery will include patients' past medical history, hemoglobin
concentration, INR, MCV, gender, age and weight.
Immediately prior to surgery, but after induction of anesthesia, subjects will have another
complete blood count drawn to assess preoperative hemoglobin/hematocrit concentrations.
This is customarily done to establish a baseline. During surgery patient's core temperature,
hemoglobin, hematocrit levels, estimated blood loss, Central Venous Pressure, blood
pressure, heart rate, cell saver, the amount of irrigation fluid, colloid, crystalloid,
blood and blood products will be recorded hourly throughout surgery. All of the data
collection described is standard in these types of cases.
Patients will be transfused allogenic blood if hemoglobin levels fall below 8.0 g/dL or
patients present with clinical signs/symptoms of hypovolemia (hypotension, tachycardia).
Data collection concerning allogenic blood transfusion will include intraoperative
transfusion rate, volume of transfused units per patient and transfusion index. Surgical
intervention data regarding the extent of the surgical procedure will be collected: the
number of curves, the curve magnitude, type of instrumentation required, the number of
levels fused and the fluoroscopy time. The placement and type of wound drains and their
.respective outputs will be noted. Preoperative and postoperative curve magnitude will be
documented as well as instrumentation used to facilitate curve correction. The number of
levels fused will be documented.
Hemoglobin and hematocrit levels will be noted at several intervals post operatively (24
hours, 48 hours and last result prior to discharge) and further transfusion requirement will
be recorded. The length of Intensive Care Unit stay and the length of hospital stay will be
noted. Regarding surgical procedure all patients will be operated on by the same surgical
team, under standardized anesthesia, total intravenous anesthesia (TIVA), and postoperative
analgesia. Data will be expressed as percentages or as a mean +/- SD. T-test analysis will
be used for comparison for quantitative variables and a p value < 0.05 will be considered
statistically significant
Inclusion Criteria:
- all patients undergoing surgical correction of scoliosis
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