Ablation of Ventricular Arrhythmias By Targeted Ablation of Reentrant Sites (AVATAR)



Status:Recruiting
Conditions:Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:21 - 90
Updated:12/23/2018
Start Date:June 2011
End Date:December 2019
Contact:David Krummen, MD
Email:dkrummen@ucsd.edu
Phone:(858) 642-3539

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Trial Summary
Trial Overview
Inclusion Criteria
This study will test the hypothesis that many human heart rhythm disorders are caused by
small localized sources, where brief ablation may successfully eliminate the heart rhythm
disorder.

The investigators will enroll patients with documented rapid heart rates from the bottom
chambers of the heart (ventricular tachyarrhythmias).

During electrophysiological study, the investigators will map the localized sources of these
heart rhythm disorders.

1. The 'active' group will prospectively receive brief ablation at localized sources (Focal
Impulse and Rotor Modulation, FIRM).

2. The control group will be a historical cohort who have received traditional ablation for
this disorder.

All patients will be followed for up to 1 year to ensure that they have no recurrent
arrhythmias.

Inclusion Criteria:

1. Documented ventricular tachyarrhythmias.

2. Undergoing clinically indicated EP study with ablation.

Exclusion Criteria:

1. Unwillingness or inability to provide informed consent.
We found this trial at
2
sites
University of California San Diego Medical Center
San Diego, California 92103
Principal Investigator: Sanjiv Narayan, MD
Phone: 858-552-8585
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Veterans Affairs San Diego Medical Center
San Diego, California 92161
Principal Investigator: Sanjiv Narayan, MD
Phone: 858-552-8585
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San Diego, CA
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