A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
| Status: | Recruiting |
|---|---|
| Conditions: | Neurology, Orthopedic, ALS |
| Therapuetic Areas: | Neurology, Orthopedics / Podiatry, Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 6/4/2016 |
| Start Date: | November 2011 |
| End Date: | December 2016 |
| Contact: | Daniela Grasso |
| Email: | dgrasso@partners.org |
| Phone: | 617-726-0842 |
A Multicenter Study for the Discovery and Validation of ALS Biomarkers
The purpose of this study is to collect biofluid samples for the banking and usage in ALS
research. Through comparison of these samples, the researchers hope to learn more about the
underlying cause of ALS, as well as find unique biological markers, which could be used to
develop new therapies.
research. Through comparison of these samples, the researchers hope to learn more about the
underlying cause of ALS, as well as find unique biological markers, which could be used to
develop new therapies.
The purpose of the research study is to collect blood samples and cerebrospinal fluid (CSF)
from people with amyotrophic lateral sclerosis (ALS). These samples will be collected
approximately every 4 months.
from people with amyotrophic lateral sclerosis (ALS). These samples will be collected
approximately every 4 months.
Inclusion Criteria:
- Age 18 or older
- Diagnosis of suspected, possible, probable or definite ALS according to El Escorial
Criteria
- Vital capacity (VC) at least 50 percent predicted
- Able to undergo multiple lumbar punctures
Exclusion Criteria:
- Abnormal CSF pressure or intracranial/intraspinal tumors
- Use of anticoagulant medication that cannot be safely withheld
- Bleeding disorders
- This is a partial listing.
We found this trial at
6
sites
4200 Fifth Ave
Pittsburgh, Pennsylvania 15260
Pittsburgh, Pennsylvania 15260
(412) 624-4141
Principal Investigator: David Lacomis, MD
Phone: 412-648-9053
University of Pittsburgh The University of Pittsburgh is a state-related research university, founded as the...
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201 Dowman Dr
Atlanta, Georgia 30303
Atlanta, Georgia 30303
(404) 727-6123
Principal Investigator: Jonathan Glass, MD
Phone: 404-778-3807
Emory University Emory University, recognized internationally for its outstanding liberal artscolleges, graduate and professional schools,...
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185 Cambridge Street
Boston, Massachusetts 02114
Boston, Massachusetts 02114
617-724-5200
Principal Investigator: James Berry, MD, MPH
Phone: 617-724-7398
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Jacksonville, Florida 32216
Principal Investigator: Kevin Boylan, MD
Phone: 904-953-9498
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Phoenix, Arizona 85013
Principal Investigator: Shafeeq Ladha, MD
Phone: 602-406-4792
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Worcester, Massachusetts 01655
Principal Investigator: Robert Brown, MD, DPhil
Phone: 508-856-4697
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