Assessing Fermentability of a Dietary Fiber
Status: | Active, not recruiting |
---|---|
Conditions: | Food Studies |
Therapuetic Areas: | Pharmacology / Toxicology |
Healthy: | No |
Age Range: | 18 - 65 |
Updated: | 7/14/2018 |
Start Date: | December 1, 2011 |
End Date: | September 1, 2019 |
Assessing Fermentability of a Dietary Fiber (FCHO) in Healthy Non-obese Men and Women
The objective of this study is to provide evidence for its fermentability of a dietary fiber
and to collect information regarding potential health opportunities for glucose control as
well as tolerability when being consumed over 7 days.
and to collect information regarding potential health opportunities for glucose control as
well as tolerability when being consumed over 7 days.
This study is designed as a randomized, 2-arm, treatment-controlled, within-subjects, 8-hour
postprandial crossover study, utilizing a multiple sampling paradigm to evaluate
fermentability and potential health opportunities for glucose control of a dietary fiber
(FCHO) in healthy non-obese men and women. The study will include 2 - 8 h assessments
following consumption of the FCHO drink or a placebo drink and will follow with a 7 day
feeding period to assess tolerability.
postprandial crossover study, utilizing a multiple sampling paradigm to evaluate
fermentability and potential health opportunities for glucose control of a dietary fiber
(FCHO) in healthy non-obese men and women. The study will include 2 - 8 h assessments
following consumption of the FCHO drink or a placebo drink and will follow with a 7 day
feeding period to assess tolerability.
Inclusion Criteria:
- 18 years of age or older
- BMI between 18.5 and 29.9 kg/m2, inclusive
- No clinical evidence of cardiovascular, metabolic, respiratory, renal,
gastrointestinal, or hepatic disease
- No diabetes
- No Gastrointestinal issues
Exclusion Criteria:
- Pregnant and/or lactating or planning for pregnancy
- Allergies or intolerances to foods consumed in the study Fasting blood glucose > 125
mg/dL.
- Vegetarian
- Taking over the counter fiber supplements or other supplements that may interfere with
the study procedures or endpoints
- Taking actively probiotics or purposely taking/ subscribing to a diet high in
prebiotics.
- Taking prescription medications that may interfere with study procedures or endpoints
(eg., antibiotics)
- Subjects with unusual dietary habits (e.g. pica)
- Actively losing weight or trying to lose weight (unstable body weight fluctuations of
> 5 kg in a 60 day period)
- Excessive exercisers or trained athletes
- Addicted to drugs and/or alcohol
- Medically documented psychiatric or neurological disturbances
- Smokers (past smokers may be allowed if cessation is > 2 years)
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