Efficacy and Safety Study of Gevokizumab to Treat Moderate to Severe Acne Vulgaris

Inclusion Criteria:

- Diagnosis of moderate to severe acne vulgaris

- Acne vulgaris unresponsive to oral antibiotics

- Willingness to maintain current habits for facial cleaning, shaving, and
application of cosmetics through the end of the study

Exclusion Criteria:

- Use of medications or treatments from specified pre-treatment time periods through
the end of the study

- Beard, moustache, sideburns or other facial hair that may interfere with evaluation

- Other forms of acne

- History of malignancy within 5 years

- History of allergic or anaphylactic reactions to monoclonal antibodies

- History of tuberculosis

- History of chronic systemic infections

- Female subjects who are pregnant, planning to become pregnant

Other protocol-defined inclusion/exclusion criteria may apply