Comparison of Temporal to Pulmonary Artery Temperature Measurement in Patients With Fever
| Status: | Completed |
|---|---|
| Conditions: | Infectious Disease |
| Therapuetic Areas: | Immunology / Infectious Diseases |
| Healthy: | No |
| Age Range: | 18 - 90 |
| Updated: | 5/5/2014 |
| Start Date: | February 2012 |
| End Date: | March 2014 |
| Contact: | Diane L Carroll, PhD, RN |
| Email: | dcarroll3@partners.org |
| Phone: | 617-724-4934 |
Assessment and evaluation of body temperature is an important sign of health and disease.
Inferior thermometry increases the risk of morbidity and mortality, and increases health
care cost by delaying the diagnosis and treatment of fever-related disease. The gold
standard for measuring core body temperature is the pulmonary artery thermistor (PAT). The
measurement of the PAT requires the insertion of the invasive pulmonary artery catheter, a
high risk procedure.
An innovative thermometry technology, the temporal artery thermometer (TAT), has been
introduced into the clinical arena as a potential non-invasive proxy for the PAT. The TAT
reduces the risk and cost of pulmonary artery catheter insertion by non-invasively measuring
core blood temperature by measuring temperature over the skin of the temporal artery.
Research to demonstrate the precision and accuracy of the TAT in normothermic patients has
been published, but little to no data is available in those with temperatures greater than
100.4oF. The purpose of this study is to measure the precision and accuracy of 2standard of
care temperature methods: the thermistor from the PAT, considered the gold standard, and the
TAT as measured in those patients with a PAT temperature greater than 100.4oF.
Inferior thermometry increases the risk of morbidity and mortality, and increases health
care cost by delaying the diagnosis and treatment of fever-related disease. The gold
standard for measuring core body temperature is the pulmonary artery thermistor (PAT). The
measurement of the PAT requires the insertion of the invasive pulmonary artery catheter, a
high risk procedure.
An innovative thermometry technology, the temporal artery thermometer (TAT), has been
introduced into the clinical arena as a potential non-invasive proxy for the PAT. The TAT
reduces the risk and cost of pulmonary artery catheter insertion by non-invasively measuring
core blood temperature by measuring temperature over the skin of the temporal artery.
Research to demonstrate the precision and accuracy of the TAT in normothermic patients has
been published, but little to no data is available in those with temperatures greater than
100.4oF. The purpose of this study is to measure the precision and accuracy of 2standard of
care temperature methods: the thermistor from the PAT, considered the gold standard, and the
TAT as measured in those patients with a PAT temperature greater than 100.4oF.
The results from previous studies agree that direct comparisons of the PAT and TAT are
clinically comparable in the normal temperature range in adults. This was defined as a
clinical significance difference of less than ±.5ºC (.9ºF. In the one study that assessed
subjects with fevers (temperatures greater than 37.8oC (100.0oF) with some methodological
criticism, compared the TAT to PAT in adults (n=15). There were poor correlations (r=0.3)
among the adult measurements with a difference of 1.3+0.6o C. Eighty-nine percent of the
TAT measurements were different than the PAT by more that ±.5ºC.
With only one study that focused in those who had a PAT outside the normal temperature range
to evaluate accuracy and precision, there is a need for further research to assess the
accuracy and precision of the TAT for detection of hyperthermia. A new onset of temperature
equal to or above 100.4oF is defined as a fever and a temperature of 100.9oF is considered a
reasonable trigger for a clinical assessment according to the Society of Critical Care
Medicine in their fever guidelines for adults. Researchers synthesizing the literature on
the TAT and other noninvasive temperature measurements, indicate that noninvasive
temperature measurements are accurate for normal temperatures but may fail to detect
hyperthermia and hypothermia, depending on the thermometer used. The authors concluded that
the TAT is clinically comparable to the PAT in only the normal temperature range.
A repeated measures design will be used to describe the accuracy and precision of 2
temperature measurements, the PAT and the TAT. Study subjects will act as their own control
in order to investigate the difference in PAT readings and the TAT readings in both the core
and oral mode. The PAT will also be compared to the TAT reading taken by the clinical staff.
clinically comparable in the normal temperature range in adults. This was defined as a
clinical significance difference of less than ±.5ºC (.9ºF. In the one study that assessed
subjects with fevers (temperatures greater than 37.8oC (100.0oF) with some methodological
criticism, compared the TAT to PAT in adults (n=15). There were poor correlations (r=0.3)
among the adult measurements with a difference of 1.3+0.6o C. Eighty-nine percent of the
TAT measurements were different than the PAT by more that ±.5ºC.
With only one study that focused in those who had a PAT outside the normal temperature range
to evaluate accuracy and precision, there is a need for further research to assess the
accuracy and precision of the TAT for detection of hyperthermia. A new onset of temperature
equal to or above 100.4oF is defined as a fever and a temperature of 100.9oF is considered a
reasonable trigger for a clinical assessment according to the Society of Critical Care
Medicine in their fever guidelines for adults. Researchers synthesizing the literature on
the TAT and other noninvasive temperature measurements, indicate that noninvasive
temperature measurements are accurate for normal temperatures but may fail to detect
hyperthermia and hypothermia, depending on the thermometer used. The authors concluded that
the TAT is clinically comparable to the PAT in only the normal temperature range.
A repeated measures design will be used to describe the accuracy and precision of 2
temperature measurements, the PAT and the TAT. Study subjects will act as their own control
in order to investigate the difference in PAT readings and the TAT readings in both the core
and oral mode. The PAT will also be compared to the TAT reading taken by the clinical staff.
Inclusion Criteria:
1. Pulmonary artery catheter in place for a clinical indication,
2. fever > 100.4oF
Exclusion Criteria:
1. significant carotid or cerebrovascular disease,
2. PA catheter is not in proper position as confirmed by chest x-ray
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