Exercise Stress CMR Comparison Study
| Status: | Completed |
|---|---|
| Conditions: | Peripheral Vascular Disease, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | August 2007 |
Comparison of Exercise MRI and Exercise Nuclear Scintigraphy in Patients With Suspected Coronary Artery Disease.
This study is being done to compare standard nuclear exercise stress testing to exercise
stress magnetic resonance imaging (MRI). The investigators have successfully shown that
exercise MRI works well in healthy volunteers, and the next step is to test if it works as
well as nuclear stress testing in patients with known or suspected heart disease.
MRIs offers superior image quality compared to echocardiography and nuclear imaging, and
have the ability to image both function and perfusion. Combining the superior image quality
of Cardiac MRI with the diagnostic information provided by exercise stress could result in a
new, more accurate modality for diagnosing and evaluating coronary artery disease.
stress magnetic resonance imaging (MRI). The investigators have successfully shown that
exercise MRI works well in healthy volunteers, and the next step is to test if it works as
well as nuclear stress testing in patients with known or suspected heart disease.
MRIs offers superior image quality compared to echocardiography and nuclear imaging, and
have the ability to image both function and perfusion. Combining the superior image quality
of Cardiac MRI with the diagnostic information provided by exercise stress could result in a
new, more accurate modality for diagnosing and evaluating coronary artery disease.
Inclusion Criteria:
- any patient referred for stress SPECT
- known or suspected ischemic heart disease
- ability to perform adequate treadmill stress
Exclusion Criteria:
- any contraindication to MRI (e.g. ferromagnetic foreign body, cerebral aneurysm clip,
pacemaker/ICD, severe claustrophobia)
- renal insufficiency (GFR <40)
- known allergy to gadolinium-based contrast or iodinated contrast (because of the
research CTA in patients not referred for cath after 2 weeks)
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