Mindfulness-Oriented Recovery Enhancement for Chronic Pain Patients Receiving Opioid Therapy



Status:Completed
Conditions:Chronic Pain
Therapuetic Areas:Musculoskeletal
Healthy:No
Age Range:18 - Any
Updated:5/5/2014
Start Date:October 2011
End Date:July 2013
Contact:Eric L Garland, PhD
Email:egarland@fsu.edu
Phone:850-645-9571

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Mindfulness-Oriented Recovery Enhancement for Chronic Pain Patients Receiving Opioid Therapy: Exploration of Cognitive, Affective, and Physiological Mechanisms

Persons suffering from chronic pain who are treated with long-term opioid therapy are at
risk of misusing prescription opioids and developing opioid addiction. Moreover, long-term
use of opioids may result in hyperalgesia, which exacerbates opioid craving and consumption.
Mindfulness interventions have been shown reduce chronic pain symptoms, addictive processes,
and substance use. The investigators hypothesize that relative to a support group control
condition, participation in a novel mindfulness-oriented cognitive intervention,
Mindfulness-Oriented Recovery Enhancement (MORE), will result in improved well-being and
decreased pain, opioid craving, and opioid misuse behaviors among chronic pain patients
receiving opioid therapy.

Few behavioral treatments target the cognitive-affective mediators of opioid misuse and
addiction in chronic pain patients. As such, novel, multimodal interventions are needed to
effectively target key mechanisms in the risk chain from chronic pain to opioid misuse and
addiction. The secondary aim of this study is to explore possible cognitive, affective, and
psychophysiological mediators of intervention effects on pain, opioid craving, opioid misuse
behaviors, and well-being.

Inclusion Criteria:

- chronic pain diagnosis (ICD-9 diagnoses 338.xx)

- treatment with prescription opioids for > 3 months

Exclusion Criteria:

- prior mindfulness training

- persons who are experiencing acute opioid withdrawal

- suicidal ideation

- psychosis
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