Pediatric Dysphagia Outcomes After Injection Laryngoplasty for Type I Laryngeal Cleft



Status:Completed
Conditions:Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:Any - 18
Updated:4/2/2016
Start Date:January 2012
End Date:June 2013
Contact:Lourdes Quintanilla-Dieck, MD
Email:quintani@ohsu.edu
Phone:(503) 494-8311

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Type I laryngeal cleft evaluation and treatment in the pediatric population is an emerging
science. The largest published series of pediatric patients with type I laryngeal clefts
shows conflicting evidence in terms of outcomes, resolution of dysphagia and method of
treatment. A comparison of quality of life outcomes before and after injection laryngoplasty
has not been carried out. The investigators hypothesize that injection laryngoplasty
significantly improves symptoms and quality of life related to dysphagia in a pediatric
population with laryngeal clefts.

Dysphagia with aspiration is a common disorder in the pediatric population. Aspiration with
feeds is diagnosed on modified barium swallow studies and patients are referred to the
pediatric otolaryngologist to assess the airway for a possible laryngeal cleft. Type I
laryngeal cleft can lead to dysphagia and aspiration in young children. However, diagnosis
of type I laryngeal cleft can be difficult and subjective at microlaryngoscopy in the
operating room. Type I laryngeal cleft evaluation and treatment in the pediatric population
is an emerging science. The largest published series of pediatric patients with type I
laryngeal clefts shows conflicting evidence in terms of outcomes, resolution of dysphagia
and method of treatment. It is generally recommended to do an injection laryngoplasty at the
time of airway evaluation as a diagnostic and therapeutic measure. Improvement in symptoms
supports the diagnosis and can serve as either definitive treatment with repeated injections
or as a preemptive treatment in preparation for surgical repair. A comparison of quality of
life outcomes before and after injection laryngoplasty has not been carried out. Thus, the
aim of this study is to determine if injection laryngoplasty improves symptoms and quality
of life related to dysphagia in a pediatric population with laryngeal clefts.

Inclusion Criteria:

- chief complaint of dysphagia and/or aspiration detected on a clinical swallow
assessment and/or modified barium swallow study

- able to withstand general anesthesia and direct microlaryngoscopy in the operating
room

Exclusion Criteria:

- inability or parent refusal to undergo procedure under general anesthesia in the
operating room
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