Prevalence and Clinical Severity of Cutaneous Lupus Erythematosus

The database has yielded valuable information and clinical insights into the
pathophysiology, disease processes, treatments and quality of life associated with CLE. The
CLE database incorporates the CLASI (Cutaneous Lupus Activity and Severity Index), a
validated outcome measure of disease responsiveness in patients and other assessment tools,
surveys and patient information to help validate the clinical course and quality of life of
patients with CLE (cutaneous lupus erythematosus).

The CLE database has led to publication of significant studies on lupus and its clinical
course, the effect of lupus on Quality of Life (QoL), including the effect of
photosensitivity on QoL, and the effect of first line medications.

The CLE database is an ongoing resource that enables clinicians to evaluate the evolving
clinical changes, treatment modalities and patient response to a challenging disease.

Inclusion Criteria:

- Subjects who meet the criteria for having CLE, using the Gilliam classifications,
and/or a diagnosis of systemic lupus erythematosus (SLE), using the American
Rheumatism Association/American College of Rheumatology criteria. Subjects must be 18
years or older.

Exclusion Criteria:

- All subjects who do not meet the criteria for having CLE. Subjects who meet the
criteria for CLE but who are not yet 18 years old