Use of Radiographic Contrast to Detect Dental Caries
| Status: | Completed |
|---|---|
| Conditions: | Other Indications, Dental |
| Therapuetic Areas: | Dental / Maxillofacial Surgery, Other |
| Healthy: | No |
| Age Range: | 19 - 99 |
| Updated: | 6/2/2016 |
| Start Date: | September 2014 |
| End Date: | May 2016 |
The Use of Radiographic Contrast to Differentiate Cavitated From Non-cavitated Dental Caries
The proposed test is intended to enable dentists to differentiate between cavitated and
non-cavitated tooth decay in the areas where teeth are in contact (interproximal surfaces).
In these areas, dentists cannot visually inspect for caries, and currently bitewing X-rays
(BWs) only correctly detect the presence of enamel decay 15-25% of the time. This low
sensitivity can lead to late treatment resulting in unnecessarily large fillings, crowns,
pain, root canals, and possible later loss of teeth.
Hypothesis: Use of radiographic contrast on teeth will increase the accuracy of detection of
early cavitation from 58% to 90%.
non-cavitated tooth decay in the areas where teeth are in contact (interproximal surfaces).
In these areas, dentists cannot visually inspect for caries, and currently bitewing X-rays
(BWs) only correctly detect the presence of enamel decay 15-25% of the time. This low
sensitivity can lead to late treatment resulting in unnecessarily large fillings, crowns,
pain, root canals, and possible later loss of teeth.
Hypothesis: Use of radiographic contrast on teeth will increase the accuracy of detection of
early cavitation from 58% to 90%.
Tooth sites will be recorded by tooth number, type of surface (mesial, distal,occlusal),
cavitated, non-cavitated, healthy. Radiographs will similarly be scored.Although contrast
agents are classified as drugs this is not a study of drug properties or effect on cells
since the properties of the agent are already well know and its safety record well
established. This study will be recording the radiopacity of the contrast agent on healthy
tooth surfaces, non-cavitated tooth surfaces and cavitated tooth surfaces. The outcome for
each surface type will be presence or absence of a radiopacity on a radiograph which will be
made at the one and only visit for each study subject. The radiograph contains the data from
the intervention (placement of contrast agent) and the outcome will be assessed some weeks
later after the completion of the data collection.
cavitated, non-cavitated, healthy. Radiographs will similarly be scored.Although contrast
agents are classified as drugs this is not a study of drug properties or effect on cells
since the properties of the agent are already well know and its safety record well
established. This study will be recording the radiopacity of the contrast agent on healthy
tooth surfaces, non-cavitated tooth surfaces and cavitated tooth surfaces. The outcome for
each surface type will be presence or absence of a radiopacity on a radiograph which will be
made at the one and only visit for each study subject. The radiograph contains the data from
the intervention (placement of contrast agent) and the outcome will be assessed some weeks
later after the completion of the data collection.
Inclusion Criteria:
- must have a minimum of 2 adjacent teeth so that interproximal surfaces of interest
are in contact and hidden from direct visual inspection.
- the occlusal plane should be normal so that the interproximal contact regions are
normal.
- English or Spanish speaker.
Exclusion Criteria:
- pregnant women
- a person who has participated in a similar study involving dental radiography within
the last 12 months.
- fillings must not be present in the regions of interest.
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