Repeating Patterns of Sleep Restriction and Recovery
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Healthy Studies |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - 35 |
| Updated: | 4/21/2016 |
| Start Date: | August 2011 |
| End Date: | June 2016 |
Repeating Patterns of Sleep Restriction and Recovery - do we Get Used to it?
Goal of this study is to test the hypothesis that repeated exposure to cycles of
insufficient sleep increases susceptibility to a variety of disease states by progressively
compromising the integrity of stress response systems.
insufficient sleep increases susceptibility to a variety of disease states by progressively
compromising the integrity of stress response systems.
Inclusion Criteria:
- Body mass index (BMI) between 18.5 and 30 kg/m2
- For female participants: regular menstrual cycles
- Daily sleep duration in the normal range
- Blood chemistry in the normal range
Exclusion Criteria:
- Active infection/disease
- History of psychiatric, neurological, pain-related, immune, or cardiovascular
disease; significant allergy
- Pregnant/nursing
- Respiratory disturbance index of >5 events/hour on polysomnographic sleep study, leg
movements with arousal >10/hour; sleep efficiency <80%
- Regular medication use other than oral contraceptives
- Donation of blood or platelets 3 month prior to or in-between study arms
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Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
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