A Double Blind Study Comparing Hyaluronic Acid, Corticosteroid and Placebo During Arthrocentesis for TMJ
| Status: | Completed |
|---|---|
| Conditions: | Chronic Pain, Orthopedic |
| Therapuetic Areas: | Musculoskeletal, Orthopedics / Podiatry |
| Healthy: | No |
| Age Range: | 18 - 90 |
| Updated: | 5/27/2016 |
| Start Date: | January 2012 |
| End Date: | April 2016 |
A Double Blind Randomised Study Comparing Hyaluronic Acid, Corticosteroid and Placebo During Arthrocentesis for Temporomandibular Joint Dysfunction
The purpose of this study is to determine whether the administration of hyaluronic acid or
corticosteroid during arthrocentesis of the temporomandibular joint provides additional pain
relief and improved function.
The overall hypothesis for the study is that hyalgan will result in a 30% reduction in the
mean visual analogue scale (VAS) at one month when compared to celestone and placebo.
corticosteroid during arthrocentesis of the temporomandibular joint provides additional pain
relief and improved function.
The overall hypothesis for the study is that hyalgan will result in a 30% reduction in the
mean visual analogue scale (VAS) at one month when compared to celestone and placebo.
This study will enroll patients with temporomandibular joint dysfunction who are deemed
appropriate candidates for irrigation of their jaw joints secondary to pain or limited
opening. At the completion of the joint irrigation subjects will be injected by one of three
different products to determine if the additional injection results in a further decrease in
jaw joint pain and improved opening. Subjects will be followed for 3 months. Those who do
not show improvement may be candidates for additional treatment.
appropriate candidates for irrigation of their jaw joints secondary to pain or limited
opening. At the completion of the joint irrigation subjects will be injected by one of three
different products to determine if the additional injection results in a further decrease in
jaw joint pain and improved opening. Subjects will be followed for 3 months. Those who do
not show improvement may be candidates for additional treatment.
Inclusion Criteria:
- age greater than 18 years
- arthralgia of one or both temporomandibular joints
- Wilkes II to IV internal derangement of the symptomatic joint OR
- limited opening of <35 mm
Exclusion Criteria:
- myofascial pain as the primary source of pain
- cervical pain as the primary source of pain
- systemic arthropathy
- fibromyalgia
- use of NSAIDS within 48 hours
- allergy to study medications
- edentulous subjects
- pregnancy or breast feeding
- current physical therapy, muscle relaxants or antiseizure medications
- current use of a splint issued within last 12 weeks
We found this trial at
5
sites
Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
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Emory University Emory University, recognized internationally for its outstanding liberal artscolleges, graduate and professional schools,...
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University of California at Los Angeles The University of California, Los Angeles (UCLA) is an...
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