High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure



Status:Completed
Conditions:Pulmonary
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:Any
Updated:5/27/2013
Start Date:June 2011
End Date:March 2013
Contact:Beatriz de Jongh, MD
Email:bdejongh@nemours.org
Phone:302-733-2410

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Trial Summary
Trial Overview
Inclusion Criteria

Pulmonary Function Testing in Infants With Respiratory Insufficiency While Receiving High Flow Nasal Cannula (HFNC) Versus Nasal Continuous Positive Airway Pressure (nCPAP)


The purpose of this study is to compare two common methods of providing respiratory support:
nasal continuous airway pressure and high flow nasal cannula to see what effect it has on
babies breathing. The investigators also will compare the effects of slightly changing the
level of support these two different types of therapy on how easily your baby is breathing.
Changes in the level of support and between these two respiratory support modalities are
frequently done and are part of the routine care in the neonatal intensive care unit.


Inclusion Criteria:

- Infants who are between 28 and 40 weeks of corrected gestational age at the time of
study entry

- Currently on high flow nasal cannula receiving 3 to 5 lpm or on nasal continuous
positive airway pressure at 5 to 6 cmH2P with and FiO2 requirement clinical care team for clinical care purposes.

- On current mode of support for >/= 12 hours and have been extubated from a mechanical
ventilator for >/= 48 hours.

Exclusion Criteria:

- Infants with skeletal or neuromuscular disorders that affect the accuracy of RIP PFT
measurements.
We found this trial at
1
site
Christiana Care Health System - Christiana Hospital
4755 Ogletown-Stanton Road
Newark, Delaware 19718
302-733-1000
Christiana Care Health System - Christiana Hospital A 913-bed, 1.3-million-square-foot, modern facility in Newark, Delaware,...
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mi
from
Newark, DE
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