Taste Perception Pre and Post Bariatric Surgery
| Status: | Completed |
|---|---|
| Conditions: | Obesity Weight Loss |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 20 - 70 |
| Updated: | 12/20/2017 |
| Start Date: | September 2009 |
| End Date: | June 2013 |
Effect of Bariatric Surgery-induced Weight Loss on Taste Perception
The investigators wish to study the effects of three forms of bariatric surgery, gastric
bypass lap banding, and sleeve gastrectomy. The surgery is not part of the clinical trial. If
your insurance does not cover the procedure, then the patient is responsible for payment of
the surgical process. The investigators are doing pre and post surgery testing to provide a
better understanding of the effect of bariatric surgery-induced weight-loss on taste
perception.
bypass lap banding, and sleeve gastrectomy. The surgery is not part of the clinical trial. If
your insurance does not cover the procedure, then the patient is responsible for payment of
the surgical process. The investigators are doing pre and post surgery testing to provide a
better understanding of the effect of bariatric surgery-induced weight-loss on taste
perception.
Bariatric surgery is the most effective weight loss therapy for obesity. However, the
mechanisms responsible for decreased food intake are incompletely understood. One possible
mechanism that could account for decreased food intake is changes in taste perception.
Therefore, the primary goal of this proposal is to provide a better understanding of the
effects of bariatric surgery-induced weight-loss on taste perception.
mechanisms responsible for decreased food intake are incompletely understood. One possible
mechanism that could account for decreased food intake is changes in taste perception.
Therefore, the primary goal of this proposal is to provide a better understanding of the
effects of bariatric surgery-induced weight-loss on taste perception.
Inclusion Criteria:
- BMI >=35 kg/m²
- on stable dose of medication for at least 4 weeks before the pre-surgery studies
- women
Exclusion Criteria:
- smokes > 7 cigarettes per day
- previous malabsorptive or restrictive intestinal surgery
- pregnant or breastfeeding
- recent history of neoplasia (< 5 years ago)
- have malabsorptive syndromes and inflammatory intestinal disease
- diabetes mellitus
- show signs of oral disease or xerostomia (i.e. dry mouth)
- history of chronic rhinitis
- on medication that might affect taste
- severe organ disfunction
We found this trial at
1
site
660 S Euclid Ave
Saint Louis, Missouri 63110
Saint Louis, Missouri 63110
(314) 362-5000
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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