PROGENI Family Study of LRRK2

Status:	Completed
Conditions:	Parkinsons Disease
Therapuetic Areas:	Neurology
Healthy:	No
Age Range:	18 - Any
Updated:	11/30/2013
Start Date:	May 2011
End Date:	May 2013
Contact:	Cheryl A Halter, MS, CCRC
Email:	progeni@iupui.edu
Phone:	888-830-6299

PROGENI Family Study

The PROGENI Family Study is part of a larger consortium that is studying a gene shown to be
important in Parkinson's disease, called LRRK2. People who have a defect in the LRRK2 gene
will often develop Parkinson's disease. Eligible participants will be asked to complete a
single Study Visit at an affiliated research facility closest to their home.

Participants will be asked to complete a family history questionnaire, which will gather
information about their family history of Parkinson's disease and related disorders. They
will be asked to complete a single Study Visit, during which they will be asked to do some
or all of the following:

1. Complete questionnaires regarding Parkinson's disease symptoms, medical history,
mood, sleep, mental status, and activity level.

2. Be given a brief standard neurological examination.

3. Be given a scratch and sniff smell identification test.

4. Be asked to give a sample of approximately 2 tablespoons of blood.

5. Be asked to give a urine sample of approximately 1 tablespoon of urine.

Inclusion Criteria:

Positive for a LRRK2 mutation

We found this trial at

sites

Cleveland Clinic Florida

2950 Cleveland Clinic Blvd.
Weston, Florida 33331

866.293.7866