Evaluating the Effect of Diabetes Control Through Intensive Lifestyle Modifications on Diabetic Peripheral Neuropathy

Inclusion Criteria:

Inclusion of Intervention group:

1. Men and Women with established Diabetes.

2. BMI between 30-45 Kg/m2

3. Age: 18-75 years old.

4. Enrolled in the Why WAIT program

5. Diabetes duration of at least 5 years

6. Hb A1C of 6.5% or higher

Inclusion of controls:

1. Men and Women with established Diabetes.

2. BMI between 30-45 Kg/m2

3. Age: 18-75 years old.

4. Diabetes duration of at least 5 years

5. Hb A1C of 6.5% or higher

Exclusion Criteria:

1. Anatomic changes that preclude the measurement of the nerve conduction: foot
deformities, open skin injuries/ulcers, amputations and placement of surgical plates
and screws in the ankle and lower leg (tibial) area.

2. Severe diabetic peripheral neuropathy as defined clinically.

3. Severe peripheral vascular disease e.g absent dorsalis pedis pulsation.

4. Recent weight loss/gain (10 pounds) during the past six months.

5. Neuropathy due to other causes other than diabetes: Alcohol abuse, Liver/Renal
disease, Toxic exposure, Inflammatory Disease, Nutritional and Vitamin deficiencies.

6. Individuals with cardiac pacemakers.

7. Women who are Pregnant or who think they might be pregnant.