Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
| Status: | Recruiting |
|---|---|
| Conditions: | Anxiety, Depression, Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 3 - 99 |
| Updated: | 3/24/2019 |
| Start Date: | September 21, 2001 |
| Contact: | Libby Jolkovsky |
| Email: | jolkovsl@mail.nih.gov |
| Phone: | (877) 646-3644 |
The Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
The purpose of this protocol is to allow for the careful screening of patients and healthy
volunteers for participation in research protocols in the Experimental Therapeutics and
Pathophysiology Lab (ETPB) at the National Institute of Mental Health (NIMH) and for the
collection of natural history data. In addition the protocol will allow clinicians to gain
more experience in the use of a variety of polysomnographic and high-density EEG recordings.
Subjects in this protocol will undergo an evaluation which may include: a psychiatric
interview; a diagnostic interview; rating scales; a medical history; a physical exam; brain
magnetic resonance imaging (MRI); electroencephalography (EEG); electrocardiography (EKG),
magnetoencephalography (MEG); blood, saliva and urine laboratory evaluation; and a request
for medical records. Subjects may also be asked to complete questionnaires about attitudes
towards research and motivation for research participation. The data collected may also be
linked with data from other mood and anxiety disorder protocols (e.g., brain imaging, DNA,
psychophysiology tests, treatment studies, etc) for the purposes of better understanding the
diagnosis, pathophysiology, and treatment response of patients with mood disorders. Parents
of minors will be interviewed. Upon conclusion of the screening process, subjects will either
be offered participation in a research protocol and will sign the appropriate informed
consent, or will be considered not appropriate for participation in research and will be
referred back into the community. The current protocol thus serves as an entry point for
individuals with mood or anxiety disorders or healthy volunteers to enter NIMH IRB approved
ETPB protocols.
volunteers for participation in research protocols in the Experimental Therapeutics and
Pathophysiology Lab (ETPB) at the National Institute of Mental Health (NIMH) and for the
collection of natural history data. In addition the protocol will allow clinicians to gain
more experience in the use of a variety of polysomnographic and high-density EEG recordings.
Subjects in this protocol will undergo an evaluation which may include: a psychiatric
interview; a diagnostic interview; rating scales; a medical history; a physical exam; brain
magnetic resonance imaging (MRI); electroencephalography (EEG); electrocardiography (EKG),
magnetoencephalography (MEG); blood, saliva and urine laboratory evaluation; and a request
for medical records. Subjects may also be asked to complete questionnaires about attitudes
towards research and motivation for research participation. The data collected may also be
linked with data from other mood and anxiety disorder protocols (e.g., brain imaging, DNA,
psychophysiology tests, treatment studies, etc) for the purposes of better understanding the
diagnosis, pathophysiology, and treatment response of patients with mood disorders. Parents
of minors will be interviewed. Upon conclusion of the screening process, subjects will either
be offered participation in a research protocol and will sign the appropriate informed
consent, or will be considered not appropriate for participation in research and will be
referred back into the community. The current protocol thus serves as an entry point for
individuals with mood or anxiety disorders or healthy volunteers to enter NIMH IRB approved
ETPB protocols.
The purpose of this protocol is to allow for the careful screening of patients and healthy
volunteers for participation in research protocols in the Experimental Therapeutics and
Pathophysiology Lab (ETPB) at the National Institute of Mental Health (NIMH) and for the
collection of natural history data. In addition the protocol will allow clinicians to gain
more experience in the use of a variety of polysomnographic and high-density EEG recordings.
Subjects in this protocol will undergo an evaluation which may include: a psychiatric
interview; a diagnostic interview; rating scales; a medical history; a physical exam; brain
magnetic resonance imaging (MRI); electroencephalography (EEG); electrocardiography (EKG),
magnetoencephalography (MEG); blood, saliva and urine laboratory evaluation; and a request
for medical records. Subjects may also be asked to complete questionnaires about attitudes
towards research and motivation for research participation. The data collected may also be
linked with data from other mood and anxiety disorder protocols (e.g., brain imaging, DNA,
psychophysiology tests, treatment studies, etc) for the purposes of better understanding the
diagnosis, pathophysiology, and treatment response of patients with mood disorders. Parents
of minors will be interviewed. Upon conclusion of the screening process, subjects will either
be offered participation in a research protocol and will sign the appropriate informed
consent, or will be considered not appropriate for participation in research and will be
referred back into the community. The current protocol thus serves as an entry point for
individuals with mood or anxiety disorders or healthy volunteers to enter NIMH IRB approved
ETPB protocols.
volunteers for participation in research protocols in the Experimental Therapeutics and
Pathophysiology Lab (ETPB) at the National Institute of Mental Health (NIMH) and for the
collection of natural history data. In addition the protocol will allow clinicians to gain
more experience in the use of a variety of polysomnographic and high-density EEG recordings.
Subjects in this protocol will undergo an evaluation which may include: a psychiatric
interview; a diagnostic interview; rating scales; a medical history; a physical exam; brain
magnetic resonance imaging (MRI); electroencephalography (EEG); electrocardiography (EKG),
magnetoencephalography (MEG); blood, saliva and urine laboratory evaluation; and a request
for medical records. Subjects may also be asked to complete questionnaires about attitudes
towards research and motivation for research participation. The data collected may also be
linked with data from other mood and anxiety disorder protocols (e.g., brain imaging, DNA,
psychophysiology tests, treatment studies, etc) for the purposes of better understanding the
diagnosis, pathophysiology, and treatment response of patients with mood disorders. Parents
of minors will be interviewed. Upon conclusion of the screening process, subjects will either
be offered participation in a research protocol and will sign the appropriate informed
consent, or will be considered not appropriate for participation in research and will be
referred back into the community. The current protocol thus serves as an entry point for
individuals with mood or anxiety disorders or healthy volunteers to enter NIMH IRB approved
ETPB protocols.
- INCLUSION CRITERIA:
Subjects must be competent to comprehend the purpose of the screening process and to
provide written informed consent and be willing to participate in NIMH IRB approved
research protocols. Minors will be asked to assent and their parents will sign the consent
form.
Subjects will undergo an evaluation which may include a psychiatric interview, medical
(including Tanner staging for minors), neurological, and laboratory examinations (as
appropriate such as EKG, EEG, renal and liver function tests, serum electrolytes,
urinalysis, HIV, hepatitis A, B, and C, blood levels of psychotropic drugs, pregnancy
testing, and urine drug screen for the presence of psychoactive drugs and drugs of abuse).
EXCLUSION CRITERIA:
Subjects should have no general medical illness that is primary (i.e., appears to be
causing the mood disorder or anxiety disorder).
Current alcohol or substance use or dependence (excluding nicotine) of sufficient magnitude
to require independent, concurrent treatment intervention (e.g., antabuse or opiate
treatment, but not including self-help groups).
Whether the minor lives with both parents or one parent, the parent(s) he/she lives with
must have legal custody. If a parent has shared custody, both parents must consent to
participate in this protocol.
We found this trial at
1
site
9000 Rockville Pike
Bethesda, Maryland 20892
Bethesda, Maryland 20892
Phone: 877-646-3644
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