Quality of Life in Barrett's Esophagus and Gastro-Esophageal Reflux Disease



Status:Terminated
Conditions:Gastroesophageal Reflux Disease , Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - Any
Updated:1/20/2018
Start Date:January 2010
End Date:December 2017

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Quality of Life in Barrett's Esophagus and GERD:GERD Symptoms, Perception of Cancer Risk, and Actual Cancer Risk

To Compare the overall quality of life of patients with no Barrett's esophagus ,
non-dysplastic Barrett's Esophagus (NDBE), Barrett's esophagus with low grade dysplasia
(LGD), and Barrett's esophagus with high grade dysplasia (HGD). We also Compare the overall
quality of life of Barrett's esophagus patients with severe gastroesophageal reflux disease
(GERD) symptoms to those with no GERD symptoms

The presence of GERD symptoms is associated with a significant decrease in quality of
life.While a diagnosis of Barrett's esophagus is also associated with a decrease in quality
of life, these studies evaluated Barrett's esophagus patients with GERD symptoms.It is
unclear whether decrements in quality of life from cancer risk in patients with Barrett's
esophagus are due to actual cancer risk or a patient's false perception.Here we Compare the
overall quality of life of patients with no Barrett's esophagus , non-dysplastic Barrett's
Esophagus (NDBE), Barrett's esophagus with low grade dysplasia (LGD), and Barrett's esophagus
with high grade dysplasia (HGD). The Investigators will also Compare the overall quality of
life of Barrett's esophagus patients with severe gastroesophageal reflux disease (GERD)
symptoms to those with no GERD symptoms. Finally the investigators will compare the overall
quality of life of patients with a perceived low risk of esophageal cancer to those with a
perceived high risk of esophageal cancer

Inclusion Criteria:

Age 18 or above

At least one of the following:

Previous diagnosis of Barrett's esophagus Presence of GERD symptoms per patient report

Exclusion Criteria:
We found this trial at
1
site
Kansas City, Missouri 64128
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from
Kansas City, MO
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