Vitamin D Supplementation in Overweight/Obese African American Adults and Youth (D-SUNNY)



Status:Completed
Conditions:Obesity Weight Loss, Other Indications, Gastrointestinal
Therapuetic Areas:Endocrinology, Gastroenterology, Other
Healthy:No
Age Range:13 - 45
Updated:2/10/2017
Start Date:November 2011
End Date:August 2015

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria
Primary Specific Aim 1: To compare the dose-responsive effects of vitamin D3
supplementations on 25(OH) D, parathyroid hormone (PTH), and serum/urine calcium.

Primary Specific Aim 2: To compare the dose-responsive effects of vitamin D3
supplementations on non-invasive vascular measures including pulse wave velocity (PWV),
flow-mediated dilation (FMD), carotid arterial compliance (CAC), carotid Intima-Media
Thickness (cIMT), and 24-hours Ambulatory Blood Pressure (ABP) monitoring as well as casual
BP.


Inclusion Criteria:

1. African-Americans (blacks)

2. Age 13-45

3. Overweight/obese (BMI ≥ 85th percentile for their age and gender for age 13-17 and
BMI ≥ 25 kg/m2 for age 18-45)

4. Relatively healthy (no medical history of any heart, lung, endocrine or malignant
disorder)

5. Non pregnant

6. Not on any medication or vitamin supplements that can influence the study outcomes

7. Serum 25 hydroxy Vitamin D (25[OH] D) levels ≤ 20 ng/ml (50 nmol/L) at the time of
screening

Exclusion Criteria:

1. Not meeting any one or more of the above criteria

2. Females who become pregnant/test positive on urine pregnancy test during the
screening or any of the testing visits

3. Anyone who is taking any multivitamin supplements that contains vitamin D
We found this trial at
1
site
Georgia Prevention Institute
Augusta, Georgia 30912
?
mi
from
Augusta, GA
Click here to add this to my saved trials