Resistance Exercise in Rheumatic Disease
| Status: | Suspended |
|---|---|
| Conditions: | Arthritis, Rheumatoid Arthritis, Cardiology, Rheumatology |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Rheumatology |
| Healthy: | No |
| Age Range: | 45 - 85 |
| Updated: | 1/6/2019 |
| Start Date: | May 2012 |
| End Date: | June 2019 |
People with rheumatic disease often have decreased strength, muscle mass, and bone mineral
density due to repeated bouts of inflammation, normal effects of aging, disuse, and
inactivity. The medications used to quell the disease process, such as prednisone, can also
have detrimental effects on body composition, strength, and functional capacity. The
investigators propose to investigate the feasibility, safety, and effects of resistance
exercise in older patients with rheumatoid arthritis (RA) and vasculitis. The unique
resistance protocol the investigators propose involves performing movements in a slow and
controlled fashion (i.e., no acceleration or use of momentum in the lifting and lowering of
the resistance) to minimize force on the joints and connective tissues. This will be
conducted in an individually-supervised environment with a new generation of exercise
equipment that will accommodate their musculoskeletal capabilities and allow for
reproducibility of the exercise protocol. The investigators intend to investigate the
feasibility, safety, musculoskeletal, and psychological effects of this resistance exercise
protocol in older patients with rheumatoid arthritis and vasculitis by testing their
strength, body composition, functional ability, mood, and quality of life before and after
this 16-week resistance exercise intervention.
density due to repeated bouts of inflammation, normal effects of aging, disuse, and
inactivity. The medications used to quell the disease process, such as prednisone, can also
have detrimental effects on body composition, strength, and functional capacity. The
investigators propose to investigate the feasibility, safety, and effects of resistance
exercise in older patients with rheumatoid arthritis (RA) and vasculitis. The unique
resistance protocol the investigators propose involves performing movements in a slow and
controlled fashion (i.e., no acceleration or use of momentum in the lifting and lowering of
the resistance) to minimize force on the joints and connective tissues. This will be
conducted in an individually-supervised environment with a new generation of exercise
equipment that will accommodate their musculoskeletal capabilities and allow for
reproducibility of the exercise protocol. The investigators intend to investigate the
feasibility, safety, musculoskeletal, and psychological effects of this resistance exercise
protocol in older patients with rheumatoid arthritis and vasculitis by testing their
strength, body composition, functional ability, mood, and quality of life before and after
this 16-week resistance exercise intervention.
Inclusion Criteria:
- diagnosis of rheumatoid arthritis OR systemic vasculitis (defined as granulomatosis
with polyangiitis, Churg-Strauss, microscopic polyangiitis, Anti-neutrophil
cytoplasmic autoantibody (ANCA)-associated vasculitis, or giant cell arteritis)
Exclusion Criteria:
- Non-English speaking
- Pregnancy
- Absolute cardiac or pulmonary contraindication to exercise
- pacemaker
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