Comparison of Pulse Hemoglobin and Pleth Variability Index
| Status: | Completed |
|---|---|
| Conditions: | Anemia |
| Therapuetic Areas: | Hematology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/6/2019 |
| Start Date: | February 2010 |
| End Date: | February 13, 2018 |
Comparison of Pulse Hemoglobin and Pleth Variability Index to Standard Methods of Guiding Intraoperative Fluid and Transfusion Management During Major Surgical Procedures.
The purpose of this study is to investigate whether a validated sensor that is able to
measure how much oxygen-carrying molecules called hemoglobin using pulse hemoglobin and Pleth
Variability Index (PVI)] are in your blood during surgery can help your doctors manage how
much fluid and possibly blood you need to get during your surgery. The hope of the study is
that the device may provide an early indication you are having bleeding and this may mean you
need to be treated with a transfusion. Our current method of checking this is by getting a
blood sample for analysis. The investigators hope is that this device may be able to alert
the clinician of the need for blood or fluids without a blood draw being needed.
measure how much oxygen-carrying molecules called hemoglobin using pulse hemoglobin and Pleth
Variability Index (PVI)] are in your blood during surgery can help your doctors manage how
much fluid and possibly blood you need to get during your surgery. The hope of the study is
that the device may provide an early indication you are having bleeding and this may mean you
need to be treated with a transfusion. Our current method of checking this is by getting a
blood sample for analysis. The investigators hope is that this device may be able to alert
the clinician of the need for blood or fluids without a blood draw being needed.
Inclusion Criteria:
- Subjects must be >18 years old;
- must be having a major surgical procedure;
- The pre-operative estimation of blood loss must be at least 15% of the total blood
volume
Exclusion Criteria:
- Does subject have hemoglobinopathy;
- cardiac arrhythmias producing irregular rhythms;
- severe pulmonary disease;
- procedures where loss of more that 10 to 15% of total blood volume is unlikely;
- subject refusal
We found this trial at
1
site
Loma Linda University
Loma Linda, California 92354
Loma Linda, California 92354
(909) 558-4000
Principal Investigator: Davinder Ramsingh, MD
Phone: 909-558-4475
Loma Linda University Loma Linda University (LLU) is a Seventh-day Adventist educational health-sciences institution with...
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