Tumor Perfusion and Hypoxia Assessed by DCE-MRI and 18F-FMISO PET as Biomarkers of Treatment Response in Cervical Cancer
| Status: | Completed |
|---|---|
| Conditions: | Cervical Cancer, Cervical Cancer, Cancer, Women's Studies |
| Therapuetic Areas: | Oncology, Reproductive |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 5/3/2014 |
| Start Date: | June 2012 |
| End Date: | June 2014 |
| Contact: | Oguz Akin, MD |
| Phone: | 212-639-3458 |
This study is to assess how patients respond to their treatment for cervical cancer. This
research does not involve a specific treatment for the cancer that will be recommended by
the doctor and may include radiation therapy and/or chemotherapy. This is a separate
research imaging study designed to assess how patients respond to their treatment for
cervical cancer.
research does not involve a specific treatment for the cancer that will be recommended by
the doctor and may include radiation therapy and/or chemotherapy. This is a separate
research imaging study designed to assess how patients respond to their treatment for
cervical cancer.
Inclusion Criteria:
- Biopsy-documented, newly-diagnosed primary cervical cancer of all histopathology
types.
- Clinically visible gross lesion (International Federation of Gynecology and
Obstetrics (FIGO) stage IB1 and above).
- Treatment (chemoradiation), DCE-MRI and 18F-FMISO PET studies will be at MSKCC.
- Patients must be an adult female 18 years of age or older.
Exclusion Criteria:
- Patients who because of general medical or psychiatric condition, or physiologic
status cannot give an informed consent.
- Patients who received prior radiation treatment to pelvis.
- Patients with contraindications to DCE-MRI (non-compatible cardiac pacemakers or
intracranial vascular clips, allergy to Gadolinium, end-stage renal disease) and/or
18F-FMISO PET.
- Patients who do not fulfill the screening criteria for safe DCE-MRI or 18F-FMISO PET
as per the Department of Radiology guidelines.
- Pregnant patients; and or patients who are breast-feeding their babies.
We found this trial at
1
site
Memorial Sloan-Kettering Cancer Center Memorial Sloan-Kettering Cancer Center — the world's oldest and largest private...
Click here to add this to my saved trials
