Study of Human Sensory Perception



Status:Completed
Conditions:Neurology, Epilepsy
Therapuetic Areas:Neurology, Other
Healthy:No
Age Range:10 - 65
Updated:2/7/2015
Start Date:March 2012
End Date:September 2014
Contact:Becky Wood
Email:becky.wood@swedish.org
Phone:206-320-7115

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A Combined fMRI and Electrophysiological Study of Human Sensory Perception

This study will help describe how the human brain works when a person sees something, hears
something, learns something, or thinks about something by recording brain activity that
occurs when the person does a series of computer tasks. This study will be offered to people
who are in the hospital to be monitored for epilepsy by using electrodes placed in the
brain. The study will record brain activity that occurs when a patient does a memory task,
for example.

Patients who have elected to have invasive electrophysiological monitoring for epileptic
activity are invited to participate in this study. While the electrodes are in place,
patients are asked to view several scenarios on a laptop computer. During these scenarios,
for example, patients are asked to click a mouse button if they see the same picture twice
in a row or to remember a film clip of a scooter ride. Trigger points in the computer
scenarios are recorded on a separate channel alongside the brain-wave activity to allow
correlation between the brain activity and the task requested in the scenario. Using this
technique, researchers can determine what areas of the brain were active during recognition
or recall activities.

Inclusion Criteria:

- Primary diagnosis of epilepsy

- Between 10 and 65 years of age

- Scheduled to undergo invasive electrophysiological monitoring as part of a clinical
evaluation for epilepsy treatment

Exclusion Criteria:

- None
We found this trial at
1
site
Seattle, Washington 98122
?
mi
from
Seattle, WA
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