Use of Whole-Body Periodic Acceleration Therapy To Aches and Pains

This is an unblinded cross-over study of whole-body periodic acceleration (WBPA) to
ascertain if this treatment modality provides symptomatic relief of pain, stiffness, and
abnormal gait and balance in a variety of conditions. The study will compare a specific
mechanism of motion, whole-body periodic acceleration (WBPA), that has been shown to
increase the release of beneficial mediators from the vascular endothelium into the
circulation, to a control condition of slow passive motion that promotes relaxation but does
not increase release of beneficial mediators into the circulation. The study tests the
efficacy and safety of a commercially available device that consists of a motion platform,
called Exer-Rest©, that is capable of producing both types of motion to be tested. In this
investigation, 15 subjects will be randomly assigned to either procedure for 10 treatments
for 2 weeks followed by a one-week "wash-out" period. Then the opposite treatment will be
employed for two weeks.

Inclusion Criteria:

Subjects qualifying for this study satisfy the following criteria:

1. Over 18 years of age;

2. Complain of either chronic pain, joint stiffness, and/or dysfunctions of gait and
balance;

3. Complaints have been annotated by a competent physician, and the subject has been
evaluated for conditions that commonly contribute to the respective symptoms;

4. Capable of completing the appropriate testing and baseline assessments, such as
quantitative electroencephalography (qEEG) and questionnaires;

5. Tolerate the motion and duration of treatment of the WBPA.

6. Be available for regular visits to the research site for the duration of the study.

Exclusion Criteria:

WBPA is contraindicated for subjects who are pregnant or who suffer with unexplained leg
pain, skin eruptions, or who have unstable spinal injuries or conditions. Subjects who
cannot tolerate the motion and duration of treatment are also excluded.