Performance-based Reinforcement to Enhance Cognitive Remediation Therapy



Status:Completed
Conditions:Psychiatric
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - 60
Updated:4/21/2016
Start Date:September 2012
End Date:December 2014

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Pilot Study of Performance-based Reinforcement to Enhance Cognitive Remediation Therapy for Substance Users

The purpose of this study is to investigate whether monetary reinforcement for performance
will enhance the effects of cognitive remediation therapy for substance users seeking
treatment at an outpatient facility.

Forty individuals seeking treatment for an alcohol or cocaine use disorder at the Substance
Abuse Treatment Unit (SATU) will be randomized to receive cognitive remediation therapy with
or without additional compensation based on performance. Participants will use the
computerized cognitive remediation program (PSSCogRehab 2012) three times per week for four
weeks. The primary outcome measure will be an improved performance on the computerized
tasks, with secondary outcomes of changes in cognitive functioning (e.g., attention,
concentration, memory) as measured by neuropsychological tests between baseline and
post-treatment.

Inclusion Criteria:

- 18 to 60 years old

- Primary Alcohol and/or Cocaine Abuse/Dependence Diagnosis

- Abstinence from all drugs/alcohol for 30 days

- Mild cognitive impairment

- Sufficiently stable and plan to commit to 4 weeks of outpatient treatment

- Fluent in English and 6th grade reading ability

Exclusion Criteria:

- Severe cognitive impairment indicative of dementia

- Untreated bipolar or psychotic disorder

- Have current legal case pending such that incarceration during 4-week study is likely
We found this trial at
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New Haven, Connecticut 06511
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