Bipolar Radiofrequency Ablation -Role in Prevention of Postoperative Atrial Fibrillation
| Status: | Completed |
|---|---|
| Conditions: | Atrial Fibrillation |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - 90 |
| Updated: | 4/21/2016 |
| Start Date: | December 2005 |
| End Date: | March 2010 |
Atrial Fibrillation (AF) is one of the most common postoperative complications after
coronary artery bypass grafting (CABG). Postoperative AF produces a substantial impact on
hospital resources with an estimated annual expenditure of over $1 billion. This includes
the cost of pharmacological treatment and the cost of the increased length of stay. The
incidence of AF is about 30-40% in CABG patients and increases with age of the patient. As
the average age of the patient that undergoes CABG surgery is increasing, it is critical to
find a way to prevent or reduce the incidence of this complication.
We propose a prospective, randomized, controlled study to determine the role of pulmonary
vein isolation by bipolar ablation in the prevention or reduction of postoperative AF. The
block- randomization plan will be used to maintain balance of the study and control arms
throughout the study.
coronary artery bypass grafting (CABG). Postoperative AF produces a substantial impact on
hospital resources with an estimated annual expenditure of over $1 billion. This includes
the cost of pharmacological treatment and the cost of the increased length of stay. The
incidence of AF is about 30-40% in CABG patients and increases with age of the patient. As
the average age of the patient that undergoes CABG surgery is increasing, it is critical to
find a way to prevent or reduce the incidence of this complication.
We propose a prospective, randomized, controlled study to determine the role of pulmonary
vein isolation by bipolar ablation in the prevention or reduction of postoperative AF. The
block- randomization plan will be used to maintain balance of the study and control arms
throughout the study.
Inclusion Criteria:
1. Patients who require an isolated elective CABG surgery on CPB.
2. Both male and female patients of age 18 years to 90 years.
Exclusion Criteria:
1. Pre existing atrial fibrillation or history of previous atrial fibrillation.
2. Inability to provide informed consent.
3. Pregnant or nursing patients.
4. Reoperative sternotomy
5. Emergency CABG surgery.
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