Safety and Pharmacokinetics Study of ODM-201 in Castrate Resistant Prostate Cancer
| Status: | Recruiting |
|---|---|
| Conditions: | Prostate Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 2/4/2013 |
| Start Date: | March 2011 |
| Contact: | V Mononen |
| Phone: | +358 10 4261 |
Safety and Pharmacokinetics of ODM-201 in Patients With Castrate Resistant Prostate Cancer: Open, Non-randomised, Uncontrolled, Multicentre, Multiple Dose Escalation Study With a Randomised Phase II Expansion Component
The purpose of this study is to evaluate safety, tolerability and pharmacokinetics of
ODM-201 in patients with castrate resistant prostate cancer.
Inclusion Criteria:
- Written informed consent
- Histologically confirmed adenocarcinoma of prostate
- Ongoing androgen deprivation therapy with a LHRH analogue or antagonist or bilateral
orchiectomy
- Progressive metastatic disease
- Adequate bone marrow, hepatic, and renal function
Exclusion Criteria:
- Known metastases in the brain
- History of other malignancy within the previous 5 years
- Known gastrointestinal disease or procedure that affects the absorption
- Not able to swallow the study drug
We found this trial at
6
sites
Cleveland Clinic Cleveland Clinic is committed to principles as presented in the United Nations Global...
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823 82nd Parkway, Suite B
Myrtle Beach, South Carolina 29572
Myrtle Beach, South Carolina 29572
(843) 449-1010 ext.268
Carolina Urologic Research Center Carolina Urologic Research Center (CURC) has been recognized both nationally and...
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