Patient-Partner Stress Management Effects on Chronic Fatigue Syndrome Symptoms and Neuroimmune Process
| Status: | Completed |
|---|---|
| Conditions: | Neurology |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 21 - 75 |
| Updated: | 12/12/2018 |
| Start Date: | October 2010 |
| End Date: | May 2017 |
Patient-Partner Stress Management Effects on CFS Symptoms and Neuroimmune Process
The purpose of this study is to test the effects of a videotelephone-delivered
patient-partner dual-focused cognitive behavioral stress management intervention on chronic
fatigue syndrome (CFS) symptoms and related psychosocial and neuroimmune processes in
patients diagnosed with chronic fatigue syndrome. Study tests the hypothesis that
videophone-delivered patient-partner cognitive behavioral stress management (T-PP-CBSM)
intervention improves patient CFS symptoms relative to a videophone-delivered patient-partner
Health Information (PP-T- HI) condition.
patient-partner dual-focused cognitive behavioral stress management intervention on chronic
fatigue syndrome (CFS) symptoms and related psychosocial and neuroimmune processes in
patients diagnosed with chronic fatigue syndrome. Study tests the hypothesis that
videophone-delivered patient-partner cognitive behavioral stress management (T-PP-CBSM)
intervention improves patient CFS symptoms relative to a videophone-delivered patient-partner
Health Information (PP-T- HI) condition.
The study tests the effects of a 10-week patient-partner focused videophone-delivered
cognitive behavioral stress management intervention (T-PP-CBSM) intervention (relaxation,
stress awareness, cognitive restructuring, coping skills training, interpersonal skills
training) versus a time-attention-matched 10-week patient-partner based videophone-delivered
health information (T-PP-HI) (health behavior education on nutrition, sleep and other
factors) in men and women with chronic fatigue syndrome (CFS) and their partners. The study
evaluates the effects of T-PP-CBSM vs T-PP-HI on patient CFS symptoms, neuroimmune
processes--diurnal cortisol regulation and immune regulation
(pro-inflammatory:anti-inflammatory cytokine ratio ([IL-1β + IL-6 + TNF-α]:[IL-13 +
IL-10])—and psychosocial functioning at 5 months and 9 months after intervention.
cognitive behavioral stress management intervention (T-PP-CBSM) intervention (relaxation,
stress awareness, cognitive restructuring, coping skills training, interpersonal skills
training) versus a time-attention-matched 10-week patient-partner based videophone-delivered
health information (T-PP-HI) (health behavior education on nutrition, sleep and other
factors) in men and women with chronic fatigue syndrome (CFS) and their partners. The study
evaluates the effects of T-PP-CBSM vs T-PP-HI on patient CFS symptoms, neuroimmune
processes--diurnal cortisol regulation and immune regulation
(pro-inflammatory:anti-inflammatory cytokine ratio ([IL-1β + IL-6 + TNF-α]:[IL-13 +
IL-10])—and psychosocial functioning at 5 months and 9 months after intervention.
Inclusion Criteria:
- men and women diagnosed with chronic fatigue syndrome
Exclusion Criteria:
- no partner
- prior psychiatric treatment for serious psychiatric disorder (e.g., psychosis,
suicidality)
- co-morbidity or medical treatment affecting the immune system
- lack of fluency in English
We found this trial at
1
site
Click here to add this to my saved trials
