Efficacy and Safety Study Comparing CD07805/47 Gel 0.5% to Azelaic Acid Gel 15% in Subjects With Erythema of Rosacea

Adult subjects with moderate to severe facial erythema of rosacea who meet
inclusion/exclusion criteria will be randomized at Baseline/Visit 1 in a 1:1 ratio to
receive either CD07805/47 gel 0.5% once daily or azelaic acid gel 15% twice daily for 15
days. Following an appropriate washout period, subjects will then switch treatments and use
the second investigational product as instructed for 15 days (according to the subject's
randomization scheme). Subjects will re-qualify based upon inclusion/exclusion prior to
Period 2 treatment.

Inclusion Criteria:

1. Subject is male or female aged 18 years or older.

2. Subject has a clinical diagnosis of facial rosacea.

3. Subject has a clinician's assessment score of moderate to severe erythema prior to
enrollment.

4. Subject has a self assessment score of moderate to severe redness prior to
enrollment.

5. Subjects with none to mild facial inflammatory lesions of rosacea prior to
enrollment.

Exclusion Criteria:

1. Female subjects who are pregnant, nursing or planning a pregnancy during the study.

2. Subjects with a condition or who are in a situation, which in the Investigator's
opinion may put a subject at risk, may confound study results, or may interfere with
a subject's participation in the study.

3. Subjects with conditions causing facial erythema which would confound the assessment
of treatment.

4. Subjects who are taking or have recently taken medications known to have interactions
with α2-adrenergic agonists.

5. Subjects with known allergies or sensitivities to one of the components of the
investigational products.