A Study Using Cone Beam CT for Head and Neck Cancer
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | January 2009 |
| End Date: | June 2016 |
A Pilot Study of Tumor and Critical Normal Tissue Motion in Head and Neck Cancer Using Cone Beam CT
Cone beam CT (computed tomography) is a developing technology which allows CT images to be
obtained while a patient is on the radiation treatment table.(A CT scan uses x-rays to
produce detailed pictures of structures in the body.) In this study, cone beam CT scans will
be obtained before individual radiation treatment sessions for head and neck cancer. The
information gathered from these scans will be used by the researchers to look at patient
movement as well as changes in the amount of normal and tumor tissue throughout the course
of radiation therapy. The researchers will use this information to create hypothetical
radiation treatment plans, which will be used as the basis for future research. The cone
beam CT scan data will not be used to alter the actual radiation treatment of any of the
patients enrolled on the study. In addition, tests of salivary output and swallowing and
questionnaires about quality of life will be made to assess how the doses of radiation
affect them.
obtained while a patient is on the radiation treatment table.(A CT scan uses x-rays to
produce detailed pictures of structures in the body.) In this study, cone beam CT scans will
be obtained before individual radiation treatment sessions for head and neck cancer. The
information gathered from these scans will be used by the researchers to look at patient
movement as well as changes in the amount of normal and tumor tissue throughout the course
of radiation therapy. The researchers will use this information to create hypothetical
radiation treatment plans, which will be used as the basis for future research. The cone
beam CT scan data will not be used to alter the actual radiation treatment of any of the
patients enrolled on the study. In addition, tests of salivary output and swallowing and
questionnaires about quality of life will be made to assess how the doses of radiation
affect them.
Inclusion Criteria:
- Patients of all ages ≥18, both sexes, and all races will be included in this study.
Pregnant females will be excluded. No other special classes of subjects (i.e.,
prisoners) will be entered.
- Patients must be diagnosed with biopsy-proven squamous cell carcinoma of the head and
neck.
- Patients must be recommended treatment with definitive radiation therapy with
concurrent chemotherapy, but without prior surgical resection of the primary tumor or
lymph nodes
- Patients must be recommended a treatment course of at least 30 radiation fractions
- Patients must sign an informed consent form approved for this purpose by the
Institutional Review Board (IRB) of the University of Michigan Hospital indicating
that they are aware that undergoing cone beam CT of the head and neck is voluntary
and has potential risks.
Exclusion Criteria:
- Patients must not have a history of prior radiation to the head or neck
We found this trial at
1
site
1500 East Medical Center Drive
Ann Arbor, Michigan 48109
Ann Arbor, Michigan 48109
800-865-1125
University of Michigan Comprehensive Cancer Center The U-M Comprehensive Cancer Center's mission is the conquest...
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