Oxidative Stress in Obstructive Sleep Apnea: Correlation of Biomarkers and Nasal CPAP Compliance



Status:Completed
Conditions:Insomnia Sleep Studies, Pulmonary
Therapuetic Areas:Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - Any
Updated:7/16/2013
Start Date:August 2011
End Date:August 2013
Contact:Amber Surian
Email:aas64@georgetown.edu

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Trial Summary
Trial Overview
Inclusion Criteria

The purpose of this study is to check blood and urine levels to further define markers/tests
in the blood and urine that would be useful in following patients with obstructive sleep
apnea and then to see if by wearing CPAP every night, these markers can be reduced. This
research is being done because currently there are no effective blood or urine markers to
determine how well CPAP is working.


The goal of this study is to further define biomarkers that would be useful in following
patients with obstructive sleep apnea and examining their response to compliance to therapy
with CPAP. To date no correlation between biomarkers of oxidative stress and compliance to
CPAP has been measured. CPAP is the most effective treatment for obstructive sleep apnea
and has been show to reduce blood pressure and decrease oxidative stress.

Inclusion Criteria:

- Men and Women over 18 years suspected of having sleep apnea

Exclusion Criteria:

- Those under 18 years or not suspected of having sleep apnea
We found this trial at
1
site
Georgetown University Hospital
3800 Reservoir Rd NW
Washington, District of Columbia 20007
(202) 444-2000
Georgetown University Hospital MedStar Georgetown University Hospital is a not-for-profit, acute-care teaching and research hospital...
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from
Washington,
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