Effect of Citrus Bioflavonoids/Vitamin E in Conjunction With Fish Oil Supplementation

Inclusion Criteria:

- men and women ≥ 18 and ≤ 72 years old

- generally healthy

- BMI > 18 and < 38

- LDL cholesterol ≥ 130 mg/dl and < 270 mg/dl

- triglycerides ≥ 150 mg/dl and < 400 mg/dl

- ability to understand and the willingness to sign a written informed consent

Exclusion Criteria:

- use of nutritional supplements and medical foods for dyslipidemia within 30 days prior
to the study

- use of omega-3 fatty acid dietary supplements within 30 days prior to the study

- use of prescription HMG-CoA reductase inhibitors, bile acid sequestrants, fibrates,
cholesterol absorption blocking agents, or niacin

- use of prescription medications and/or nonprescription medications for acute and
semi-acute medical conditions

- history of cardiovascular disease, type i diabetes, autoimmune disease, liver or
kidney disease, malignancy, and serious mental illness.

- known infection with HIB, TB, hepatitis B or hepatitis C

- history of allergy or intolerance to study products

- smoking, use of nicotine-containing products, or use of drugs of abuse 30 days prior
to the study

- history of regular intake of > 14 alcoholic drinks per week for females and > 21
drinks per week for males