A Registry to Evaluate Patterns of Care Associated With the Use of Corus CAD (or ASGES) in Primary Care Settings

The prospective PRESET Registry (NCT01677156) enrolled stable, nonacute adult patients
presenting with typical or atypical symptoms suggestive of obstructive coronary artery
disease from 21 US primary care practices from August 2012 to August 2014. Demographics,
clinical characteristics, and Corus CAD (Age/Sex/Gene Expression score - ASGES) results
(predefined as low [ASGES <15] or elevated [ASGES >15]) were collected, as were referrals to
Cardiology or further functional/anatomic cardiac testing after Corus CAD (Age/Sex/Gene
Expression score - ASGES) testing. Patients were followed for 1 year post ASGES testing.

Inclusion Criteria:

1. Symptoms suggestive of CAD, according to the opinion of the site registry clinician

2. Receiving Corus CAD (ASGES) to aid in the diagnosis of obstructive CAD

3. Age >= 18 years

4. Willing and able to provide written informed consent

Exclusion Criteria:

1. History of myocardial infarction (MI)

2. Current MI or acute coronary syndrome

3. Current New York Heart Association (NYHA) class III or IV congestive heart failure
symptoms

4. Known/documented CAD

5. Diabetes Mellitus