Environmental Polymorphisms Registry Health and Exposures Survey
| Status: | Completed |
|---|---|
| Conditions: | Asthma, Peripheral Vascular Disease, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 9/2/2018 |
| Start Date: | August 25, 2012 |
| End Date: | November 22, 2016 |
The Environmental Polymorphisms Registry (EPR) Health and Exposure Survey is designed to
gather health, family history of disease, environmental exposures and lifestyle data on adult
EPR subjects. The EPR is a registry established to collect and store DNA samples from 20,000
volunteers from North Carolina and to serve as a resource to scientist investigating
genotype-driven translational research of chronic conditions. Under this new protocol, we
will administer a health and exposures survey to all EPR subjects. The information collected
in the survey will be used to better characterize the EPR population thus making it more
useful to NIEHS researchers. The survey contains approximately 200 questions. Data from the
survey will help researchers develop hypotheses, design follow-up studies, and select
appropriate subjects.
The survey will be administered to EPR subjects using a modified version of the Dillman Total
Design Method (TDM) for surveys. This method requires following specific time-dependent steps
for survey administration that incorporate both self- and phone administration and other
types of phone and mail contact. The goal of TDM is to maximize subject response rates.
gather health, family history of disease, environmental exposures and lifestyle data on adult
EPR subjects. The EPR is a registry established to collect and store DNA samples from 20,000
volunteers from North Carolina and to serve as a resource to scientist investigating
genotype-driven translational research of chronic conditions. Under this new protocol, we
will administer a health and exposures survey to all EPR subjects. The information collected
in the survey will be used to better characterize the EPR population thus making it more
useful to NIEHS researchers. The survey contains approximately 200 questions. Data from the
survey will help researchers develop hypotheses, design follow-up studies, and select
appropriate subjects.
The survey will be administered to EPR subjects using a modified version of the Dillman Total
Design Method (TDM) for surveys. This method requires following specific time-dependent steps
for survey administration that incorporate both self- and phone administration and other
types of phone and mail contact. The goal of TDM is to maximize subject response rates.
The Environmental Polymorphisms Registry (EPR) Health and Exposure Survey is designed to
collect health, family history of disease, environmental exposures and lifestyle data on EPR
participants. The EPR was established to collect and store DNA specimens from 20,000
participants and to serve as a resource for scientists investigating genotype-driven
translational research of chronic health conditions. Under this protocol, we will administer
the approximately 200 question Health and Exposure Survey to EPR participants. The
information will be used to better characterize the EPR population, thus making it more
useful in answering research questions related to gene-environment interactions. Data from
the survey will help researchers to advance clinical research by developing new ways of
preventing, diagnosing, and treating common diseases such as cardiovascular disease, asthma,
and diabetes.
During Phases I and II, the survey was administered to EPR participants using a modified
version of the Dillman Total Design Method (TDM) for surveys. This method requires following
specific steps for survey administration that incorporate web-based, paper and phone
administration. The rationale for using the TDM is to maximize participant response rates.
During Phase III, the survey may be distributed to new EPR participants (e.g., those who were
not enrolled in the EPR at the time of the Phase I and II survey administrations) for
self-administration at the time of enrollment.
Investigators may select and contact participants for follow-up studies based upon health,
exposure, or disease status information; this includes responses to the EPR Health and
Exposure Survey. Participation in follow-up studies is completely voluntary. Participants can
decide at the time they are contacted if they would like to enroll in the follow-up study.
Their decision whether or not to participate in a follow-up study will not affect their
participation in the EPR.
collect health, family history of disease, environmental exposures and lifestyle data on EPR
participants. The EPR was established to collect and store DNA specimens from 20,000
participants and to serve as a resource for scientists investigating genotype-driven
translational research of chronic health conditions. Under this protocol, we will administer
the approximately 200 question Health and Exposure Survey to EPR participants. The
information will be used to better characterize the EPR population, thus making it more
useful in answering research questions related to gene-environment interactions. Data from
the survey will help researchers to advance clinical research by developing new ways of
preventing, diagnosing, and treating common diseases such as cardiovascular disease, asthma,
and diabetes.
During Phases I and II, the survey was administered to EPR participants using a modified
version of the Dillman Total Design Method (TDM) for surveys. This method requires following
specific steps for survey administration that incorporate web-based, paper and phone
administration. The rationale for using the TDM is to maximize participant response rates.
During Phase III, the survey may be distributed to new EPR participants (e.g., those who were
not enrolled in the EPR at the time of the Phase I and II survey administrations) for
self-administration at the time of enrollment.
Investigators may select and contact participants for follow-up studies based upon health,
exposure, or disease status information; this includes responses to the EPR Health and
Exposure Survey. Participation in follow-up studies is completely voluntary. Participants can
decide at the time they are contacted if they would like to enroll in the follow-up study.
Their decision whether or not to participate in a follow-up study will not affect their
participation in the EPR.
- ELIGIBILITY CRITERIA:
There are no clinical exclusion criteria for this Survey. All subjects will be administered
the Survey regardless of having clinical conditions.
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