Understanding and Discouraging Overuse of Potentially Harmful Screening Tests



Status:Completed
Conditions:Prostate Cancer, Colorectal Cancer, Cancer, Cancer, Osteoporosis
Therapuetic Areas:Oncology, Rheumatology
Healthy:No
Age Range:50 - 85
Updated:4/21/2016
Start Date:September 2012
End Date:June 2014

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Most prevention efforts focus on promoting services (e.g. vaccination, screening tests).
While some of these services have clear net benefit, many instead have possible or clear net
harm. Currently, three quarters of services graded by the U.S. Preventive Services Task
Force (USPSTF) have possible or clear net harm (C, I, and D services). Many of these
services are delivered in healthcare settings at higher rates than what might be expected
based on their potential for harm. This leads to adverse outcomes, excess costs, and missed
opportunities to deliver more quality care. An important issue in delivering prevention
messages is how to shift toward a focus on the appropriateness of prevention: encouraging
services with clear net benefit and either discouraging or reducing demand for services with
possible or clear net harm. Unfortunately, little is known about what drives overuse of
potentially harmful screening services or how to make harms relevant to patients.

This randomized controlled trial (RCT) of 775 patients at 4 primary care practices aims to
1) assess factors associated with intent to receive possibly or clearly harmful screening
services and 2) determine whether and how patients' plans to get screened change with
various presentations of information about harms (e.g. qualitative, quantitative, narrative,
framed). The investigators will focus on three types of screening services: osteoporosis
screening (previous C recommendation and now no recommendation for women < 65 years old with
no fracture risk factors), prostate-specific antigen (PSA) screening (D recommendation for
all men, regardless of age), and colorectal cancer (CRC) screening (C for ages 76-85).


Inclusion Criteria:

- Women between ages 50 to 85

- Men between ages 50 to 85

- Eligible for exemplar service of interest (see below for specifics of
inclusion/exclusion for specific services)

Exclusion Criteria:

- Current treatment of psychosis

- History of alcohol or substance abuse within the last 2 years

- Dementia or other severe cognitive dysfunction

- serious medical illnesses with a life expectancy of less than 2 years (e.g.,
metastatic cancer)

- inability to speak and understand English

- blindness

- presentation for an acute medical visit

- no telephone number

Osteoporosis Screening (women aged 50-64)

Exclusion Criteria:

- a personal history of osteoporosis

- a personal history of moderate or severe osteopenia

- BMI (body mass index) < 18.5

- personal history of non-traumatic fracture

- family history of hip fracture

- current smoking

- current use of prednisone (>30 consecutive days)

- alcohol use of 3 or more drinks/day.

Prostate Cancer screening (men aged 50-69)

Exclusion Criteria:

- a prior history of prostate cancer

Colorectal Cancer Screening (men and women aged 76-85)

Exclusion Criteria:

- prior history of colorectal cancer

- adenomatous colon polyps > 6mm (or 2 or more < 6mm)

- symptoms referable to colorectal cancer
We found this trial at
1
site
Durham, North Carolina 27704
?
mi
from
Durham, NC
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