Confocal Analysis of Corneal Structures of Symptomatic Allergic Conjunctivitis Patients

Heidelberg Retina Tomograph (HRT) will be used to descriptively evaluate the corneal
structures and assess the immune cell status of allergic conjunctivitis patients pre and
post treatment with olopatadine 0.2% in relation to a normative database.

Inclusion Criteria:

- Read, sign, and date an Ethics Committee reviewed and approved informed consent form.

- Females of childbearing potential who:

- Are not breast-feeding;

- Do not intend to become pregnant for the duration of the study;

- Are using adequate birth control methods and agree to continue for the duration
of the study.

- Able to read, understand and answer questions by investigator.

- Willing and able to attend all required study visits and follow directions as
stipulated by the protocol and investigator.

- History of allergic conjunctivitis (within the past 12 months) and active signs and
symptoms of ocular allergies for which treatment is necessary, in the opinion of the
investigator.

- Visual acuity correctable to 20/30 (Snellen) or better in each eye at distance with
or without glasses correction.

- Ocular health within normal limits as determined by the investigator.

- No contact lens wear 14 days prior to enrollment and willing to not wear contact
lenses for the duration of the study.

- Willing to follow a 14-day washout period due to contraindicated medication use, if
deemed necessary by investigator.

- Other protocol-defined inclusion criteria may apply.

Exclusion Criteria:

- Contraindications or hypersensitivity to the use of the test article or its
components.

- Inability or unwillingness to follow all study instructions and complete study visits
as required.

- Only one sighted eye or visual acuity not correctable to 20/30 (Snellen) in both eyes
at the Screening Visit.

- Ocular trauma within 6 months prior to Visit 1 in either eye.

- Any ocular surgical intervention within six months prior to Visit 1 or anticipation
of ocular surgery during the study.

- Presumed or actual ocular infection within 30 days prior to Visit 1.

- Any severe or serious ocular condition or significant illness.

- Any abnormal slit-lamp findings at the time of the Screening Visit.

- Contact lens wear within 14 days prior to the study start and unwillingness to
undergo a wash-out period of 14 days; unwilling to not wear contact lenses for the
duration of the study.

- Use of over-the-counter (OTC) ocular medications within the past 14 days unless
willing to follow wash out period.

- Use of topical or systemic ocular medications requiring longer than a two-week
washout period.

- Participation in any other investigational study in the 30-day period before entry
into this study (i.e., Visit 1) or concomitantly with this study.

- Women who are pregnant, nursing, or of childbearing potential not utilizing adequate
birth control measures.

- Other protocol-defined exclusion criteria may apply.