Lung Cancer Screening Study With Low-dose CT Scan and Blood Biomarker
| Status: | Recruiting |
|---|---|
| Conditions: | Lung Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 50 - 75 |
| Updated: | 4/2/2016 |
| Start Date: | May 2012 |
| End Date: | May 2016 |
| Contact: | Melanie Phillips, BS |
| Email: | phillipsm@njhealth.org |
| Phone: | 303-398-1921 |
Different Strategies Using Autoantibodies and/or CT Scan Detection of Lung Cancer
Lung cancer is the number one cancer killer in the USA. Early stage lung cancer is
asymptomatic. Most patients with lung cancer are usually symptomatic at diagnosis and
already have advanced stage disease. Low dose CT screening (LDCT) for high risk individuals
has recently been shown to decrease lung cancer mortality by 20%. However, 4 out of 5 lung
cancer deaths are not prevented with LDCT screening alone.
asymptomatic. Most patients with lung cancer are usually symptomatic at diagnosis and
already have advanced stage disease. Low dose CT screening (LDCT) for high risk individuals
has recently been shown to decrease lung cancer mortality by 20%. However, 4 out of 5 lung
cancer deaths are not prevented with LDCT screening alone.
In this trial, the addition of a blood biomarker test is being combined with early LDCT to
determine if screening with combination may result in detection of more lung cancer at an
earlier stage of disease.The study will also assess if the blood test is able to detect lung
cancers in high risk individuals when the LDCT is negative for cancer. There will be
health-economic costs included in the final analysis of study data.
determine if screening with combination may result in detection of more lung cancer at an
earlier stage of disease.The study will also assess if the blood test is able to detect lung
cancers in high risk individuals when the LDCT is negative for cancer. There will be
health-economic costs included in the final analysis of study data.
Inclusion Criteria:
- Smokers or former smokers
- At least 20 pack year history of smoking
- Ages 50 - 75
Exclusion Criteria:
- Had a CT scan of chest within last 24 months
- History of any cancer within 10 yrs (except skin cancer or cervical cancer)
- A serious illness that decreases life expectancy to less than 5 years
- Any current use of Oxygen
- Uncontrolled congestive heart failure or cardiac arrhythmia that would prevent
surgery for a lung lesion
- Severe COPD or dyspnea that would prevent lung surgery or stereotactic body
radiotherapy
We found this trial at
1
site
National Jewish Health National Jewish Health is known worldwide for treatment of patients with respiratory,...
Click here to add this to my saved trials
