A Safety Study to Evaluate the Use and Effectiveness of a Topical Ointment to Treat Adults With Atopic Dermatitis

Inclusion Criteria:

- Adult subjects 18-65 years of age

- Diagnosis of atopic dermatitis (AD)

- AD affecting at least 5% of total Body Surface Area (BSA) for Part 1 and at least 10%
BSA for Part 2, not including face, neck, and head

- Have had a positive but inadequate response to one or more treatment course of
standard AD therapy including topical steroids, UV light A, narrowband UV B, and UV
light B.

Exclusion Criteria:

- Females pregnant or breast-feeding

- Sexually active subjects who are not practicing acceptable birth control methods

- Use of systemic or topical therapy for contact or atopic dermatitis within 30 days of
screening

- Phototherapy within 30 days of screening

- Use of oral or topical antihistamines within 7 days of first dose.