Collagen Injections for the Treatment of Acne Scars and Wrinkles

Inclusion Criteria:

- Age 18 or over

- Bilateral acne scars or have moderate to severe wrinkles

- Subjects in good health

- Subjects has the willingness and the ability to understand and provide informed
consent for the use of their tissue and communicate with the investigator

Exclusion Criteria:

- Under 18 years of age

- Pregnancy or lactation

- recent Accutane use in the past 6 months

- prone to hypertrophic and keloidal scarring

- have excessively redundant skin in the treatment area or wrinkles longer than 20 cm
total

- have a history of autoimmune disorders, organ transplantation, cancer not in
remission, active or chronic skin disease

- have a history of basal-cell carcinoma

- have previously received autologous fibroblast treatment

- have undergone any confounding therapy in the lower two-thirds of the face within 1
year or any investigational treatment within 30 days.

- have an allergy to collagen, bovine products, local anesthetics, gentamicin, or
amphotericin B

- subjects who are unable to understand the protocol or to give informed consent

- subjects with mental illness