Evaluation of Coagulation in Multiple Sclerosis
| Status: | Completed |
|---|---|
| Conditions: | Neurology, Multiple Sclerosis |
| Therapuetic Areas: | Neurology, Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 7/29/2017 |
| Start Date: | October 2012 |
| End Date: | May 2016 |
A Cross-Sectional Study of Coagulation in Multiple Sclerosis
Recent research in multiple sclerosis (MS) have suggested that altered coagulation and
vascular inflammation may play a role in pathophysiology of MS. Sonoclot is viscoelastic
method of analyzing clot formation. This instrument will be used to compare coagulation in
individuals with MS to healthy controls. A 24-hour dietary recall and food frequency
questionnaire will help determine whether coagulation is modified by fish consumption.
vascular inflammation may play a role in pathophysiology of MS. Sonoclot is viscoelastic
method of analyzing clot formation. This instrument will be used to compare coagulation in
individuals with MS to healthy controls. A 24-hour dietary recall and food frequency
questionnaire will help determine whether coagulation is modified by fish consumption.
This case-control study will recruit individuals with a diagnosis of MS and healthy controls.
Individuals will be asked to come to Bastyr Clinical Research Center for a single study
visit, at which time dietary intake, current medications and supplements, other medical
diagnoses, and coagulation will be evaluated.
Individuals will be asked to come to Bastyr Clinical Research Center for a single study
visit, at which time dietary intake, current medications and supplements, other medical
diagnoses, and coagulation will be evaluated.
Inclusion Criteria:
- Diagnosis of clinically probable of clinically definite multiple sclerosis made by
board certified neurologist. Subject must be willing to release medical information
regarding diagnosis
- Controls must consider themselves healthy and be free of any neurological, autoimmune,
endocrine or other chronic disease. Must also be free of any recent acute
illness/injury that can influence inflammatory activity.
- Individuals must be 18 or older
Exclusion Criteria:
- Diagnosis of coagulation defect
- Use of anticoagulants (eg. warfarin, coumadin) or Aspirin within 30 days of entry.
- NSAID within 7 days of entry (dietary intake of fish oil or tumeric is acceptable)
- Pregnancy
We found this trial at
1
site
Kenmore, Washington 98028
Principal Investigator: Laurie K Mischley, ND
Phone: 425-602-3306
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