A Study of Brentuximab Vedotin in Adults Age 60 and Above With Newly Diagnosed Hodgkin Lymphoma (HL)
| Status: | Recruiting |
|---|---|
| Conditions: | Lymphoma |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 60 - Any |
| Updated: | 4/3/2019 |
| Start Date: | October 2012 |
| End Date: | July 2021 |
| Contact: | Seattle Genetics Trial Information Support |
| Email: | clinicaltrials@seagen.com |
| Phone: | 866-333-7436 |
A Phase 2 Open-label Study of Brentuximab Vedotin in Front-line Therapy of Hodgkin Lymphoma (HL) in Adults Age 60 and Above
This is an open-label, multicenter, phase 2 clinical trial designed to evaluate the efficacy
and safety of brentuximab vedotin as a single-agent (Part A) and in combination with
dacarbazine (Part B), bendamustine (Part C), or nivolumab (Part D) in front-line therapy of
HL in adults age 60 and above.
and safety of brentuximab vedotin as a single-agent (Part A) and in combination with
dacarbazine (Part B), bendamustine (Part C), or nivolumab (Part D) in front-line therapy of
HL in adults age 60 and above.
Inclusion Criteria:
- Histopathologically-confirmed diagnosis of classical Hodgkin lymphoma
- Ineligible for or have declined initial conventional combination chemotherapy
- Measurable disease of at least 1.5 cm as documented by radiographic technique
- ECOG performance status less than or equal to 3
Exclusion Criteria:
- Symptomatic neurologic disease compromising instrumental activities of daily living or
requiring medication
- Concurrent use of other investigational agents
- Chemotherapy, radiotherapy, biologics, and/or other treatment with immunotherapy not
completed 4 weeks prior to first dose of study drug
We found this trial at
24
sites
6410 Rockledge Dr #660
Bethesda, Maryland 20817
Bethesda, Maryland 20817
(301) 571-0019
Principal Investigator: Ralph Boccia, MD
Phone: 301-571-2016
Center for Cancer & Blood Disorders Widely recognized for its compassionate, expert care, the Center...
Click here to add this to my saved trials
1720 2nd Ave S
Birmingham, Alabama 35233
Birmingham, Alabama 35233
(205) 934-4011
Principal Investigator: Amitkumar Mehta, MD
Phone: 205-996-8400
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
Click here to add this to my saved trials
601 Elmwood Avenue
Rochester, New York 14642
Rochester, New York 14642
(585) 275-5830
Principal Investigator: Jonathan Friedberg, MD
Phone: 585-273-3903
James P. Wilmot Cancer Center at University of Rochester Medical Center The Wilmot Cancer Center...
Click here to add this to my saved trials
Albany, New York 12206
Principal Investigator: Lawrence Garbo, MD
Phone: 281-863-6658
Click here to add this to my saved trials
Aurora, Colorado 80012
Principal Investigator: John Burke, MD
Phone: 281-863-6658
Click here to add this to my saved trials
Bedford, Texas 76022
Principal Investigator: Henrik Illum, MD
Phone: 281-863-6658
Click here to add this to my saved trials
Blacksburg, Virginia 24060
Principal Investigator: Jerome Goldschmidt, MD
Phone: 281-863-6658
Click here to add this to my saved trials
Burbank, California 91505
Principal Investigator: Ravi M. Shankar, MD
Phone: 818-748-4726
Click here to add this to my saved trials
Denton, Texas 76210
Principal Investigator: Charles Kurkul, MD
Phone: 940-382-1022
Click here to add this to my saved trials
1500 East Duarte Road
Duarte, California 91010
Duarte, California 91010
626-256-HOPE (4673)
Principal Investigator: Matthew Mei, MD
Phone: 626-256-4673
City of Hope National Medical Center City of Hope is dedicated to making a difference...
Click here to add this to my saved trials
Eugene, Oregon 97401
Principal Investigator: Christopher Yasenchak, MD
Phone: 281-863-6658
Click here to add this to my saved trials
8503 Arlington Blvd., Ste. 400
Fairfax, Virginia 22031
Fairfax, Virginia 22031
(703) 280-5390
Principal Investigator: Dipti Patel-Donnelly, MD
Phone: 281-863-6658
Virginia Cancer Specialists, PC Now the world's most advanced cancer treatment capabilities can be found...
Click here to add this to my saved trials
Fort Worth, Texas 76104
Principal Investigator: Robert L. Ruxer, MD
Phone: 281-863-6658
Click here to add this to my saved trials
Greenville, South Carolina 29605
Principal Investigator: Jeffrey Giguere
Phone: 281-863-6658
Click here to add this to my saved trials
Longview, Texas 75601
Principal Investigator: Matei Socoteanu, MD
Phone: 281-863-6658
Click here to add this to my saved trials
Minneapolis, Minnesota 55405
Principal Investigator: Timothy Larson, MD
Phone: 281-863-6658
Click here to add this to my saved trials
Niles, Illinois 60714
Principal Investigator: Leonard Klein, MD
Phone: 281-863-6658
Click here to add this to my saved trials
Omaha, Nebraska 68114
Principal Investigator: Ralph Hauke, MD
Phone: 281-863-6658
Click here to add this to my saved trials
1250 E. Marshall St.
Richmond, Virginia 23298
Richmond, Virginia 23298
(804) 828-9000
Principal Investigator: Victor Yazbeck, MD
Phone: 804-628-1909
Virginia Commonwealth University Medical Center The Virginia Commonwealth University Health System is an urban, comprehensive...
Click here to add this to my saved trials
Round Rock, Texas 78665
Principal Investigator: Vivian Cline-Burkhardt, MD
Phone: 281-863-6658
Click here to add this to my saved trials
Sandy Springs, Georgia 30341
Principal Investigator: Rodolfo Bordoni, MD
Phone: 770-496-9400
Click here to add this to my saved trials
Seattle, Washington 98104
Principal Investigator: John Pagel
Phone: 206-215-1426
Click here to add this to my saved trials
Tualatin, Oregon 97062
Principal Investigator: Kathryn Kolibaba, MD
Phone: 281-863-6658
Click here to add this to my saved trials
Tucson, Arizona 85704
Principal Investigator: Donald Brooks, MD
Phone: 281-863-6658
Click here to add this to my saved trials