Study of the Efficacy and Safety of LY2940094 in Participants With Major Depressive Disorder (MDD)

Inclusion Criteria:

- Have a diagnosis of Major Depressive Disorder (MDD) without psychotic features as
defined in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition,
Text Revision (DSM-IV-TR)

- Have clinically significant depressive symptoms defined by a GRID HAMD17 Total score
≥20 at screening

- Body mass index (BMI) between 18 and 35 kilogram per square meter (kg/m^2)

Exclusion Criteria:

- Have a current or previous diagnosis of bipolar I or II disorder, MDD with psychotic
features, schizoaffective disorder, schizophrenia, or other psychotic disorder

- Currently meeting the criteria of treatment-resistant depression defined as ≥2
documented, failed treatment trials of adequate dose and duration with a registered
antidepressant during the current depressive episode

- Had electroconvulsive treatment, transcranial magnetic stimulation, vagal nerve
stimulation for symptoms of depression in the 6 months prior to screening

- Have any clinically significant medical or uncontrolled condition or circumstance
prior to randomization that could affect participant safety