To Determine if a Lower Extremity Strengthening Program Improve Quadriceps Muscle Strength



Status:Completed
Conditions:Pulmonary
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - 75
Updated:2/7/2015
Start Date:March 2010
End Date:January 2014
Contact:Mieczyslawa Franczyk, PT, PhD
Email:mieczyslawa.franczyk@uchospitals.edu
Phone:773-702-6891

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Does The Lower Extremity Resistance Program Improve Quadriceps Strength, Endurance, And Quality Life In Pre-Lung Transplant Patients?

The purpose of this study is to determine if a lower extremity strengthening program as part
of pulmonary rehabilitation will improve quadriceps muscle strength, endurance and
functional status as well as overall quality of life.

Hypothesis:

1. Lower extremity resistance training as part of a pulmonary rehabilitation program will
improve quadriceps strength, endurance and functional capacity.

2. Lower extremity resistance training as part of a pulmonary rehabilitation program will
improve quality of life in patients awaiting lung transplant.

Objectives:

1. To determine if a lower extremity strengthening program as part of pulmonary
rehabilitation is effective at increasing quadriceps strength when measured with a hand
held dynamometer.

2. To determine the effectiveness of a lower extremity strengthening program as part of
pulmonary rehabilitation for improving endurance and functional capacity as measured by
the six minute walk test.

3. To determine if the lower extremity strengthening program as part of pulmonary
rehabilitation improves overall quality of life as measured by the St. George's
Respiratory Questionnaire.

4. To provide a basic framework for a larger randomized control study evaluating if a
lower extremity strengthening program as part of a pulmonary rehabilitation program is
more effective than a pulmonary rehabilitation program alone at improving quadriceps
strength, endurance, and functional level.

Inclusion Criteria:

- Patients preparing for lung transplant

- Diagnoses included are: Chronic Obstructive Pulmonary Disease, Idiopathic Pulmonary
Fibrosis, Sarcoidosis, Cystic Fibrosis, or Bronchiectasis

Exclusion Criteria:

- Primary Pulmonary Hypertension

- Multi-organ transplant patients

- Re-transplant patients

- Patients requiring intubation greater than or equal to 7 days prior to transplant

- Any orthopedic condition which will prevent from participation in a lower extremity
strengthening program
We found this trial at
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5841 S Maryland Ave
Chicago, Illinois 60637
(773) 702-1000
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