Phosphorous Magnetic Resonance Spectroscopy of Heart
| Status: | Completed |
|---|---|
| Conditions: | Healthy Studies, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Start Date: | June 2009 |
| End Date: | June 2015 |
| Contact: | Adil Bashir |
| Phone: | 314-362-7403 |
31P Magnetic Resonance Spectroscopy of Heart
Heart needs constant supply of energy to continue working. Phosphorus magnetic resonance
spectroscopy allows us to measure energy produced in the heart. The purpose of this study is
to determine if the energy production is reduced in failing heart.
spectroscopy allows us to measure energy produced in the heart. The purpose of this study is
to determine if the energy production is reduced in failing heart.
We will use non-invasive phosphorus magnetic resonance spectroscopy technique to measure
creatine kinase (CK) flux in failing heart. The studies will be done on Siemens 3.0T human
system. We will recruit subjects with LV dysfunction due to prior anterior wall myocardial
infarction.
creatine kinase (CK) flux in failing heart. The studies will be done on Siemens 3.0T human
system. We will recruit subjects with LV dysfunction due to prior anterior wall myocardial
infarction.
Inclusion Criteria:
- Individuals with left ventricular dysfunction
Exclusion Criteria:
- Age < 18, pregnant, history of excessive alcohol use, or any condition (e.g.
claustrophobia, a pacemaker) that would prevent him/her from completing the magnetic
resonance spectroscopy study
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