Systane Balance - Inflammatory Markers

Inclusion Criteria:

- Read, sign, and date the Informed Consent Document;

- Willing and able to follow instructions and maintain the appointment schedule;

- Must not have used any topical ocular drops for approximately 24 hours prior to Visit
1;

- Meet the protocol-specified dry eye criteria at Screening Visit (Visit 1);

- Willing to use study drugs 4 times per day in both eyes;

- Willing to discontinue use of other artificial tear products and other eyedrops;

- Intraocular pressure less than or equal to 22 mmHg in both eyes;

- Other protocol-defined inclusion criteria may apply.

Exclusion Criteria:

- History or evidence of ocular or intraocular surgery or serious trauma in either eye
within the past six months;

- Current punctal occlusion of any type (e.g., collagen plugs, silicone plugs);

- History of intolerance or hypersensitivity to any component of the study medications;

- History or evidence of epithelial herpes simplex keratitis (dendritic keratitis);
vaccinia; active or recent varicella viral disease of the cornea and/or conjunctiva;
chronic bacterial disease of the cornea and/or conjunctiva and/or eyelids;
mycobacterial infection of the eye; and/or fungal disease of the eye;

- Use of any concomitant topical ocular medications during the study period;

- Currently using Restasis and unwilling to discontinue its use 1 month prior to
screening and for the entire study period;

- Use of systemic medications that may contribute to dry eye unless on a stable dosing
regimen for a minimum of 30 days prior to Visit 1;

- Uncontrolled ocular conditions such as uveitis, glaucoma or any other ocular
condition that may preclude the safe administration of either drop under
investigation;

- Unwilling to discontinue contact lens wear during the study period and for at least
one week prior to Visit 1;

- Participation in an investigational drug or device study within 30 days of entering
this study;

- Pregnant or lactating women;

- Monocular or legally blind;

- Other protocol-defined exclusion criteria may apply.