Effect of Beta-Alanine on Heart Rate Response



Status:Completed
Conditions:Other Indications
Therapuetic Areas:Other
Healthy:No
Age Range:18 - 35
Updated:3/30/2013
Start Date:January 2013
End Date:December 2013
Contact:Smith-Ryan
Email:abbiesmith@unc.edu
Phone:919-962-2574

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The Effect of 28 Days of Beta-alanine Supplementation on the Physical Working Capacity at Heart Rate Threshold (PWCHRT)


Beta-alanine, as a method to increase muscle carnosine, has been shown to enhance muscle
buffering capacity and delay fatigue. Various fatigue tests have been utilized to examine
the effectiveness of beta-alanine supplementation. The physical working capacity test has
been used to show significant increases in physical working capacities following
supplementation. The physical working capacity tests were originally developed by Moritani
et al. 1981 and Devries et al. 1982 to measure the point of onset of muscular fatigue. It is
hypothesized that beta-alanine will increase physical working capacity at heart rate
threshold, thereby signifying a delay in fatigue.


An equal number of men and women will be recruited [Men, n=20 (10 placebo [PL]; 10
beta-alanine (Active)]; [Women,n=20 (10 PL; 10 Active)]. Men and women will be randomly
assigned to respective groups to allow for equal numbers in supplement and placebo groups.

Inclusion Criteria:

- Between the ages of 18-35 years old

- Be recreationally active (defined as accumulating 1-5 hours of moderate intensity

Exclusion Criteria

- Any health risks or indicators that would prevent them from participating in physical
activity, as determined by a health history questionnaire

- Must not have taken performance enhancing supplements containing beta-alanine or
creatine during the last 3 months
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