A Study of LY2940680 in Healthy Participants
| Status: | Completed |
|---|---|
| Conditions: | Healthy Studies |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 2/4/2013 |
| Start Date: | January 2013 |
| End Date: | March 2013 |
| Contact: | This is a single site clinical trial. 1-877-CTLILLY (1-877-285-4559) or |
| Phone: | 1-317-615-4559 |
Disposition of [14C]-LY2940680 Following Oral Administration in Healthy Subjects
This is a single dose study of radiolabelled LY2940680 taken by mouth in healthy
participants to study how the body absorbs and removes LY2940680 from the blood. This study
is for research purposes only and is not intended to treat any medical condition.
Inclusion Criteria:
- Generally healthy sterile males or surgically sterile females or postmenopausal
females, as determined by medical history and laboratory assessments
- Have a body mass index (BMI) of 18.5 to 32.0 kilograms per meter squared (kg/m^2),
inclusive
Exclusion Criteria:
- Regularly use known drugs of abuse and/or show positive findings on urinary drug
screening
- Have consumed herbal supplements, grapefruit juice, grapefruits, grapefruit
containing products, Seville orange juice, Seville oranges, star fruit, or star fruit
juice within 7 days prior to dosing or intend to consume during the study have
donated blood of more than 500 milliliters (mL) within the last month
- Have participated in a [14C]-study within the last 6 months prior to admission for
this study
- Exposure to significant radiation within 12 months prior to dose (for example, serial
X-ray or computed tomography scans, barium meal, current employment in a job
requiring radiation exposure monitoring)
- Have a pattern less than once per 2 days to expel feces from the bowel through the
rectum or acute constipation within 3 weeks of the day prior to dose
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